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Protective Effect of Triclosan in Monocrotaline-Induced Pulmonary Arterial Hypertension: FASN Inhibition a Novel Approach

BACKGROUND: Novel pharmacological approaches are needed to improve the outcomes of patients with idiopathic pulmonary hypertension. Fatty acid synthase (FASN) inhibitors have shown beneficial effects in preclinical models of pulmonary arterial hypertension (PAH), because of their role in the regulat...

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Detalles Bibliográficos
Autores principales: Alsabeelah, Nimer, Kumar, Vinay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10084994/
https://www.ncbi.nlm.nih.gov/pubmed/37051426
http://dx.doi.org/10.4103/jpbs.jpbs_307_22