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Recombinant Adenovirus-Mediated HIF-lα Ameliorates Neurological Dysfunction by Improving Energy Metabolism in Ischemic Penumbra After Cerebral Ischemia-Reperfusion in Rats

BACKGROUND: Hypoxia inducible factor-1α (HIF-1α) regulates glucose metabolism during ischemia. This study investigated the effect of recombinant adenovirus HIF-1ɑ on neurological function and energy metabolism in a rat cerebral ischemia-reperfusion model. METHODS: Rats were divided into four groups:...

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Detalles Bibliográficos
Autores principales:	Zhou, Wenmei, Tao, Tao, Yu, Wenfeng, Wu, Wanfu, Hui, Zhirong, Xu, Hongliang, Li, Yaqi, Zhang, Ying, Yang, Xiaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085005/ https://www.ncbi.nlm.nih.gov/pubmed/37051416 http://dx.doi.org/10.2147/NDT.S389022

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