Myeloid-specific fatty acid transport protein 4 deficiency induces a sex-dimorphic susceptibility for nonalcoholic steatohepatitis in mice fed a high-fat, high-cholesterol diet

Newborns with FATP4 mutations exhibit ichthyosis prematurity syndrome (IPS), and adult patients show skin hyperkeratosis, allergies, and eosinophilia. We have previously shown that the polarization of macrophages is altered by FATP4 deficiency; however, the role of myeloid FATP4 in the pathogenesis...

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Detalles Bibliográficos
Autores principales: Göcebe, Deniz, Jansakun, Chutima, Zhang, Yuling, Staffer, Simone, Tuma-Kellner, Sabine, Altamura, Sandro, Muckenthaler, Martina U., Merle, Uta, Herrmann, Thomas, Chamulitrat, Walee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085558/
https://www.ncbi.nlm.nih.gov/pubmed/36881564
http://dx.doi.org/10.1152/ajpgi.00181.2022

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