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Renoprotective effects of empagliflozin are linked to activation of the tubuloglomerular feedback mechanism and blunting of the complement system

The mechanisms of nephroprotection in nondiabetic chronic kidney disease (CKD) models by sodium-glucose cotransporter 2 (SGLT2) inhibitors are not well defined. Five groups were established: sham-operated rats, placebo-treated rats with 5/6 nephrectomy (5/6Nx), 5/6Nx + telmisartan (5 mg/kg/day), 5/6...

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Detalles Bibliográficos
Autores principales:	Chen, Xin, Delić, Denis, Cao, Yaochen, Shen, Linghong, Shao, Qin, Zhang, Zheyu, Wu, Hongwei, Hasan, Ahmed A., Reichetzeder, Christoph, Gaballa, Mohamed M. S., Krämer, Bernhard K., Klein, Thomas, Yin, Lianghong, He, Ben, Morgera, Stanislao, Hocher, Berthold
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085567/ https://www.ncbi.nlm.nih.gov/pubmed/36779666 http://dx.doi.org/10.1152/ajpcell.00528.2022

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