Cargando…

The cell senescence regulator p16 is a promising cancer prognostic and immune check-point inhibitor (ICI) therapy biomarker

Cyclin-dependent kinase inhibitor 2A (CDKN2A) encodes the cell senescence regulator protein p16. The expression of p16 raises in cell senescence and has a nuclear regulation in cell aging. Meanwhile, it's also reported to inhibit the aggression of several cancers. But its clinical application a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tu, Zewei, Wang, Xiaolin, Cai, Huan, Sheng, Yilei, Wu, Lei, Huang, Kai, Zhu, Xingen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085592/ https://www.ncbi.nlm.nih.gov/pubmed/36961395 http://dx.doi.org/10.18632/aging.204601

Ejemplares similares

Protein Disulfide-Isomerase A3 Is a Robust Prognostic Biomarker for Cancers and Predicts the Immunotherapy Response Effectively
por: Tu, Zewei, et al.
Publicado: (2022)

Comprehensive analysis of the prognostic implications and functional exploration of PAK gene family in human cancer
por: Lei, Kunjian, et al.
Publicado: (2022)

Bioactive Glass (BG) ICIE16 Shows Promising Osteogenic Properties Compared to Crystallized 45S5-BG
por: Westhauser, Fabian, et al.
Publicado: (2020)

Integrin Alpha-2 as a Potential Prognostic and Predictive Biomarker for Patients With Lower-Grade Glioma
por: Lin, Li, et al.
Publicado: (2021)

Synthesis of novel ICIE16/BSG and ICIE16/BSG-NITRI bioglasses and description of ionic release kinetics upon immersion in SBF fluid: Effect of nitridation
por: Orgaz, Felipe, et al.
Publicado: (2015)

Comprehensive analysis of the prognostic and role in immune cell infiltration of MSR1 expression in lower‐grade gliomas
por: Ji, Qiankun, et al.
Publicado: (2022)

Development and validation of a leukocyte‐associated immunoglobulin‐like receptor‐1 prognostic signature for lower‐grade gliomas
por: Fang, Zhansheng, et al.
Publicado: (2022)

N6-Methylandenosine-Related lncRNAs Are Potential Biomarkers for Predicting the Overall Survival of Lower-Grade Glioma Patients
por: Tu, Zewei, et al.
Publicado: (2020)

The Association Between Inflammation and Immunosuppression: Implications for ICI Biomarker Development
por: Sacdalan, Danielle Benedict, et al.
Publicado: (2021)

ICIS05 CONFERENCE
por: Lau, C, et al.
Publicado: (02/1)

The Icy Realm of the Rime
por: Potter, Polyxeni
Publicado: (2011)

Ferroptosis-related gene signature correlates with the tumor immune features and predicts the prognosis of glioma patients
por: Hu, Yan, et al.
Publicado: (2021)

Systematic and Multi-Omics Prognostic Analysis of Lysine Acetylation Regulators in Glioma
por: Tu, Zewei, et al.
Publicado: (2021)

PTPRD mutation is a prognostic biomarker for sensitivity to ICIs treatment in advanced non-small cell lung cancer
por: Ren, Zhixuan, et al.
Publicado: (2023)

Recognizing Prognostic and Predictive Biomarkers in the Treatment of Non-Small Cell Lung Cancer (NSCLC) with Immune Checkpoint Inhibitors (ICIs)
por: Giustini, Nicholas, et al.
Publicado: (2021)

Enceladus and the icy moons of Saturn
por: Schenk, Paul M, et al.
Publicado: (2018)

Ici, priorité ... aux piétons !
Publicado: (2002)

L'espion d'ici
por: Omnes, Roland
Publicado: (2000)

Pan-cancer analysis of N4-acetylcytidine adaptor THUMPD1 as a predictor for prognosis and immunotherapy
por: Li, Kuangxun, et al.
Publicado: (2021)

Transcriptional Patterns of Lower-Grade Glioma Patients with Distinct Ferroptosis Levels, Immunotherapy Response, and Temozolomide Sensitivity
por: Tu, Zewei, et al.
Publicado: (2022)

Protein disulfide-isomerase A4 confers glioblastoma angiogenesis promotion capacity and resistance to anti-angiogenic therapy
por: Tu, Zewei, et al.
Publicado: (2023)

Clinical characteristics and treatment efficacy of immune checkpoint inhibitors (ICIs) in patients with ICIs-induced Adrenal insufficiency
por: Xiang, Jing, et al.
Publicado: (2023)

Increased Pro-Inflammatory T Cells, Senescent T Cells, and Immune-Check Point Molecules in the Placentas of Patients With Gestational Diabetes Mellitus
por: Kang, Yea Eun, et al.
Publicado: (2022)

Tracking Actomyosin at Fluorescence Check Points
por: Lard, Mercy, et al.
Publicado: (2013)

ICIS workshop on adnexal mass characterization
por: Rockall, Andrea
Publicado: (2014)

How to Detect Life on Icy Moons
por: Sephton, Mark A., et al.
Publicado: (2018)

Thermal picks for anchoring on icy moons
por: Halperin, Adam H., et al.
Publicado: (2019)

Intravesical ICIs to reduce toxicity in NMIBC
por: Masone, Maria Chiara
Publicado: (2022)

Prognostic and Predictive Value of Immune-Related Gene Pair Signature in Primary Lower-Grade Glioma Patients
por: Lei, Kunjian, et al.
Publicado: (2021)

Predictive Biomarkers for Outcomes of Immune Checkpoint Inhibitors (ICIs) in Melanoma: A Systematic Review
por: Baltussen, Joosje C., et al.
Publicado: (2021)

Sperm Autoantigenic Protein 17 Predicts the Prognosis and the Immunotherapy Response of Cancers: A Pan-Cancer Analysis
por: Tu, Zewei, et al.
Publicado: (2022)

Immune Check Point Inhibitor–Associated Glomerulonephritis
por: Ashour, Tarek, et al.
Publicado: (2018)

Immune Check Point Inhibitor–Associated Endothelialitis
por: Bobart, Shane A., et al.
Publicado: (2020)

Check(point) or checkmate for acute myeloid leukemia?
por: Niyongere, Sandrine, et al.
Publicado: (2021)

Response in post-menopausal patients on ICI 118630.
por: Robertson, J. F., et al.
Publicado: (1987)

Integrated science in digital age: icis 2019
por: Antipova, Tatiana
Publicado: (2019)

Nouvelles d'ici et d'ailleurs /
Publicado: (1987)

An Icy Vista from a Golden Age
por: Breedlove, Byron
Publicado: (2018)

ICIs-Related Cardiotoxicity in Different Types of Cancer
por: Dong, Mei, et al.
Publicado: (2022)

First-line ICIs in renal cell carcinoma
por: Fiorentino, Vincenzo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4m9ua25un494k0b04cvc0v4v8b