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PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway

Cartilage endplate (CEP) degeneration and calcification is an important contributor to the onset and pathogenesis of intervertebral disc degeneration (IDD). However, the underlying mechanisms of CEP degeneration remain elusive, let alone according treatment strategies to prevent CEP degeneration. Ph...

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Detalles Bibliográficos
Autores principales:	Cui, Xingang, Liu, Xiaoyang, Kong, Peng, Du, Ting, Li, Tao, Yang, Guihe, Zhang, Weimin, Jing, Xingzhi, Wang, Wenchao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085618/ https://www.ncbi.nlm.nih.gov/pubmed/36971687 http://dx.doi.org/10.18632/aging.204612

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