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Crystal structures of the NAD(+)-II riboswitch reveal two distinct ligand-binding pockets
We present crystal structures of a new NAD(+)-binding riboswitch termed NAD(+)-II, bound to nicotinamide mononucleotide (NMN), nicotinamide adenine dinucleotide (NAD(+)) and nicotinamide riboside (NR). The RNA structure comprises a number of structural features including three helices, one of which...
Autores principales: | Peng, Xuemei, Liao, Wenjian, Lin, Xiaowei, Lilley, David M J, Huang, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085692/ https://www.ncbi.nlm.nih.gov/pubmed/36840714 http://dx.doi.org/10.1093/nar/gkad102 |
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