Structural and functional insights into the activation of the dual incision activity of UvrC, a key player in bacterial NER

Bacterial nucleotide excision repair (NER), mediated by the UvrA, UvrB and UvrC proteins is a multistep, ATP-dependent process, that is responsible for the removal of a very wide range of chemically and structurally diverse DNA lesions. DNA damage removal is performed by UvrC, an enzyme possessing a...

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Detalles Bibliográficos
Autores principales: Seck, Anna, De Bonis, Salvatore, Stelter, Meike, Ökvist, Mats, Senarisoy, Müge, Hayek, Mohammad Rida, Le Roy, Aline, Martin, Lydie, Saint-Pierre, Christine, Silveira, Célia M, Gasparutto, Didier, Todorovic, Smilja, Ravanat, Jean-Luc, Timmins, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085695/
https://www.ncbi.nlm.nih.gov/pubmed/36869664
http://dx.doi.org/10.1093/nar/gkad108

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