SMAD3 promotes expression and activity of the androgen receptor in prostate cancer

Overexpression of androgen receptor (AR) is the primary cause of castration-resistant prostate cancer, although mechanisms upregulating AR transcription in this context are not well understood. Our RNA-seq studies revealed that SMAD3 knockdown decreased levels of AR and AR target genes, whereas SMAD...

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Detalles Bibliográficos
Autores principales: Jeon, Hee-Young, Pornour, Majid, Ryu, Hyunju, Khadka, Sudeep, Xu, Rui, Jang, Jihyun, Li, Deqiang, Chen, Hegang, Hussain, Arif, Fazli, Ladan, Gleave, Martin, Dong, Xuesen, Huang, Furong, Wang, Qianben, Barbieri, Christopher, Qi, Jianfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085708/
https://www.ncbi.nlm.nih.gov/pubmed/36727462
http://dx.doi.org/10.1093/nar/gkad043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085708/
https://www.ncbi.nlm.nih.gov/pubmed/36727462
http://dx.doi.org/10.1093/nar/gkad043

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