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Polycomb response elements reduce leaky expression of Cas9 under temperature-inducible Hsp70Bb promoter in Drosophila melanogaster

Heat-shock-inducible expression of genes through the use of heat-inducible promoters is commonly used in research despite leaky expression of downstream genes of interest without targeted induction (i.e. heat shock). The development of non-leaky inducible expression systems is of broad interest for...

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Detalles Bibliográficos
Autores principales:	Warsinger-Pepe, Natalie, Chang, Carly, Desroberts, Connor R, Akbari, Omar S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085756/ https://www.ncbi.nlm.nih.gov/pubmed/36705519 http://dx.doi.org/10.1093/g3journal/jkad024

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