Concomitant TP53 mutation in early-stage resected EGFR-mutated non-small cell lung cancer: a narrative approach in a genetically admixed Brazilian cohort

TP53 mutations are frequent in non-small cell lung cancer (NSCLC) and have been associated with poor outcome. The prognostic and predictive relevance of EGFR/TP53 co-mutations in NSCLC is controversial. We analyzed lung tissue specimens from 70 patients with NSCLC using next-generation sequencing to...

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Detalles Bibliográficos
Autores principales: Machado-Rugolo, J., Baldavira, C.M., Prieto, T.G., Olivieri, E.H.R., Fabro, A.T., Rainho, C.A., Castelli, E.C., Ribolla, P.E.M., Ab'Saber, A.M., Takagaki, T., Nagai, M.A., Capelozzi, V.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085757/
https://www.ncbi.nlm.nih.gov/pubmed/37042869
http://dx.doi.org/10.1590/1414-431X2023e12488

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