Integrative modeling of tumor genomes and epigenomes for enhanced cancer diagnosis by cell-free DNA

Multi-cancer early detection remains a key challenge in cell-free DNA (cfDNA)-based liquid biopsy. Here, we perform cfDNA whole-genome sequencing to generate two test datasets covering 2125 patient samples of 9 cancer types and 1241 normal control samples, and also a reference dataset for background...

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Detalles Bibliográficos
Autores principales: Bae, Mingyun, Kim, Gyuhee, Lee, Tae-Rim, Ahn, Jin Mo, Park, Hyunwook, Park, Sook Ryun, Song, Ki Byung, Jun, Eunsung, Oh, Dongryul, Lee, Jeong-Won, Park, Young Sik, Song, Ki-Won, Byeon, Jeong-Sik, Kim, Bo Hyun, Sohn, Joo Hyuk, Kim, Min Hwan, Kim, Gun Min, Chie, Eui Kyu, Kang, Hyun-Cheol, Kong, Sun-Young, Woo, Sang Myung, Lee, Jeong Eon, Ryu, Jai Min, Lee, Junnam, Kim, Dasom, Ki, Chang-Seok, Cho, Eun-Hae, Choi, Jung Kyoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085982/
https://www.ncbi.nlm.nih.gov/pubmed/37037826
http://dx.doi.org/10.1038/s41467-023-37768-3

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