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Alteration of gut microbiota in wild-borne long-tailed macaques after 1-year being housed in hygienic captivity
The wild-born long-tailed macaques (Macaca fascicularis) were recently recruited and used as breeders for the National Primate Research Center of Thailand, Chulalongkorn University (NPRCT-CU), and changes in their in-depth gut microbiota profiles were investigated. The Oxford Nanopore Technology (ON...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085984/ https://www.ncbi.nlm.nih.gov/pubmed/37037869 http://dx.doi.org/10.1038/s41598-023-33163-6 |
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author | Sawaswong, Vorthon Chanchaem, Prangwalai Kemthong, Taratorn Warit, Saradee Chaiprasert, Angkana Malaivijitnond, Suchinda Payungporn, Sunchai |
author_facet | Sawaswong, Vorthon Chanchaem, Prangwalai Kemthong, Taratorn Warit, Saradee Chaiprasert, Angkana Malaivijitnond, Suchinda Payungporn, Sunchai |
author_sort | Sawaswong, Vorthon |
collection | PubMed |
description | The wild-born long-tailed macaques (Macaca fascicularis) were recently recruited and used as breeders for the National Primate Research Center of Thailand, Chulalongkorn University (NPRCT-CU), and changes in their in-depth gut microbiota profiles were investigated. The Oxford Nanopore Technology (ONT) was used to explore full-length 16S rDNA sequences of gut microbiota in animals once captured in their natural habitat and 1-year following translocation and housing in a hygienic environment at NPRCT-CU. Our findings show that the gut microbiota of macaques after 1 year of hygienic housing and programmed diets feeding was altered and reshaped. The prevalent gut bacteria such as Prevotella copri and Faecalibacterium prausnitzii were enriched after translocation, causing the lower alpha diversity. The correlation analysis revealed that Prevotella copri, Phascolarctobacterium succinatutens, and Prevotella stercorea, showed a positive correlation with each other. Significantly enriched pathways in the macaques after translocation included biosynthesis of essential amino acids, fatty acids, polyamine and butanoate. The effects of microbiota change could help macaques to harvest the energy from programmed diets and adapt their gut metabolism. The novel probiotics and microbiota engineering approach could be further developed based on the current findings and should be helpful for captive animal health care management. |
format | Online Article Text |
id | pubmed-10085984 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-100859842023-04-12 Alteration of gut microbiota in wild-borne long-tailed macaques after 1-year being housed in hygienic captivity Sawaswong, Vorthon Chanchaem, Prangwalai Kemthong, Taratorn Warit, Saradee Chaiprasert, Angkana Malaivijitnond, Suchinda Payungporn, Sunchai Sci Rep Article The wild-born long-tailed macaques (Macaca fascicularis) were recently recruited and used as breeders for the National Primate Research Center of Thailand, Chulalongkorn University (NPRCT-CU), and changes in their in-depth gut microbiota profiles were investigated. The Oxford Nanopore Technology (ONT) was used to explore full-length 16S rDNA sequences of gut microbiota in animals once captured in their natural habitat and 1-year following translocation and housing in a hygienic environment at NPRCT-CU. Our findings show that the gut microbiota of macaques after 1 year of hygienic housing and programmed diets feeding was altered and reshaped. The prevalent gut bacteria such as Prevotella copri and Faecalibacterium prausnitzii were enriched after translocation, causing the lower alpha diversity. The correlation analysis revealed that Prevotella copri, Phascolarctobacterium succinatutens, and Prevotella stercorea, showed a positive correlation with each other. Significantly enriched pathways in the macaques after translocation included biosynthesis of essential amino acids, fatty acids, polyamine and butanoate. The effects of microbiota change could help macaques to harvest the energy from programmed diets and adapt their gut metabolism. The novel probiotics and microbiota engineering approach could be further developed based on the current findings and should be helpful for captive animal health care management. Nature Publishing Group UK 2023-04-10 /pmc/articles/PMC10085984/ /pubmed/37037869 http://dx.doi.org/10.1038/s41598-023-33163-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Sawaswong, Vorthon Chanchaem, Prangwalai Kemthong, Taratorn Warit, Saradee Chaiprasert, Angkana Malaivijitnond, Suchinda Payungporn, Sunchai Alteration of gut microbiota in wild-borne long-tailed macaques after 1-year being housed in hygienic captivity |
title | Alteration of gut microbiota in wild-borne long-tailed macaques after 1-year being housed in hygienic captivity |
title_full | Alteration of gut microbiota in wild-borne long-tailed macaques after 1-year being housed in hygienic captivity |
title_fullStr | Alteration of gut microbiota in wild-borne long-tailed macaques after 1-year being housed in hygienic captivity |
title_full_unstemmed | Alteration of gut microbiota in wild-borne long-tailed macaques after 1-year being housed in hygienic captivity |
title_short | Alteration of gut microbiota in wild-borne long-tailed macaques after 1-year being housed in hygienic captivity |
title_sort | alteration of gut microbiota in wild-borne long-tailed macaques after 1-year being housed in hygienic captivity |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085984/ https://www.ncbi.nlm.nih.gov/pubmed/37037869 http://dx.doi.org/10.1038/s41598-023-33163-6 |
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