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RNF2 inhibits E-Cadherin transcription to promote hepatocellular carcinoma metastasis via inducing histone mono-ubiquitination

RNF2 is a RING domain-containing E3 ubiquitin ligase that mediate histone H2A mono-ubiquitination to repress gene transcription, but its expression patterns and molecular function in hepatocellular carcinoma (HCC) remain unclear. Herein, we extracted data from TGCA database and validated RNF2 expres...

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Detalles Bibliográficos
Autores principales: Yao, Lei, Li, Jun, Jiang, Bo, Zhang, Zeyu, Li, Xinying, Ouyang, Xiwu, Xiao, Yao, Liu, Guodong, Wang, Zhiming, Zhang, Gewen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085990/
https://www.ncbi.nlm.nih.gov/pubmed/37037816
http://dx.doi.org/10.1038/s41419-023-05785-1

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