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RNF2 inhibits E-Cadherin transcription to promote hepatocellular carcinoma metastasis via inducing histone mono-ubiquitination
RNF2 is a RING domain-containing E3 ubiquitin ligase that mediate histone H2A mono-ubiquitination to repress gene transcription, but its expression patterns and molecular function in hepatocellular carcinoma (HCC) remain unclear. Herein, we extracted data from TGCA database and validated RNF2 expres...
Autores principales: | Yao, Lei, Li, Jun, Jiang, Bo, Zhang, Zeyu, Li, Xinying, Ouyang, Xiwu, Xiao, Yao, Liu, Guodong, Wang, Zhiming, Zhang, Gewen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10085990/ https://www.ncbi.nlm.nih.gov/pubmed/37037816 http://dx.doi.org/10.1038/s41419-023-05785-1 |
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