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Synthesis, radiolabeling, and evaluation of a (4-quinolinoyl)glycyl-2-cyanopyrrolidine analogue for fibroblast activation protein (FAP) PET imaging

Fibroblast activation protein (FAP) is regarded as a promising target for the diagnosis and treatment of tumors as it was overexpressed in cancer-associated fibroblasts. FAP inhibitors bearing a quinoline scaffold have been proven to show high affinity against FAP in vitro and in vivo, and the scaff...

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Detalles Bibliográficos
Autores principales:	Zhang, Ni, Pan, Fei, Pan, Lili, Diao, Wei, Su, Feijing, Huang, Rui, Yang, Bo, Li, Yunchun, Qi, Zhongzhi, Zhang, Wenjie, Wu, Xiaoai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086185/ https://www.ncbi.nlm.nih.gov/pubmed/37057133 http://dx.doi.org/10.3389/fbioe.2023.1167329

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