Bruceine a exerts antitumor effect against colon cancer by accumulating ROS and suppressing PI3K/Akt pathway

Bruceine A (BA), a quassic ester from bruceine javanica, regulates diverse intracellular signal transduction pathways and manifests a variety of biological activities, however, its pharmacological mechanism in treating colon cancer (CC) is unclear. In this study, we investigated the anticancer effec...

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Detalles Bibliográficos
Autores principales: Zhang, Chaozheng, Cao, Yuening, Zuo, Yi, Cheng, Hongbin, Liu, Changqun, Xia, Xila, Ren, Bo, Deng, Yun, Wang, Maolin, Lu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086190/
https://www.ncbi.nlm.nih.gov/pubmed/37056992
http://dx.doi.org/10.3389/fphar.2023.1149478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086190/
https://www.ncbi.nlm.nih.gov/pubmed/37056992
http://dx.doi.org/10.3389/fphar.2023.1149478

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