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Graves’ disease: moving forwards

Graves’ disease is a rare disorder that continues to present clinicians and families with a series of challenges. There are no new established treatments for children or adolescents, but the outcomes of recent clinical trials and meta-analyses have helped clinicians to prepare families for the road...

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Detalles Bibliográficos
Autores principales: Lane, Laura C, Wood, Claire Louise, Cheetham, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086272/
https://www.ncbi.nlm.nih.gov/pubmed/35831126
http://dx.doi.org/10.1136/archdischild-2022-323905
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author Lane, Laura C
Wood, Claire Louise
Cheetham, Tim
author_facet Lane, Laura C
Wood, Claire Louise
Cheetham, Tim
author_sort Lane, Laura C
collection PubMed
description Graves’ disease is a rare disorder that continues to present clinicians and families with a series of challenges. There are no new established treatments for children or adolescents, but the outcomes of recent clinical trials and meta-analyses have helped clinicians to prepare families for the road ahead. We have a more refined understanding of how to administer antithyroid drugs, which one to use and how long to treat the young person. We also have a greater insight into how best to reduce any risks associated with surgery and radioiodine. We understand more about long-term outcomes and their determinants and have greater awareness about the impact of the disease and its treatment on quality of life. A holistic approach to management is key to supporting and counselling young people and their families about the diagnosis and management options. In this review, we will discuss the recent literature and reflect on how this should be translated into clinical practice.
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spelling pubmed-100862722023-04-12 Graves’ disease: moving forwards Lane, Laura C Wood, Claire Louise Cheetham, Tim Arch Dis Child Review Graves’ disease is a rare disorder that continues to present clinicians and families with a series of challenges. There are no new established treatments for children or adolescents, but the outcomes of recent clinical trials and meta-analyses have helped clinicians to prepare families for the road ahead. We have a more refined understanding of how to administer antithyroid drugs, which one to use and how long to treat the young person. We also have a greater insight into how best to reduce any risks associated with surgery and radioiodine. We understand more about long-term outcomes and their determinants and have greater awareness about the impact of the disease and its treatment on quality of life. A holistic approach to management is key to supporting and counselling young people and their families about the diagnosis and management options. In this review, we will discuss the recent literature and reflect on how this should be translated into clinical practice. BMJ Publishing Group 2023-04 2022-07-13 /pmc/articles/PMC10086272/ /pubmed/35831126 http://dx.doi.org/10.1136/archdischild-2022-323905 Text en © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
spellingShingle Review
Lane, Laura C
Wood, Claire Louise
Cheetham, Tim
Graves’ disease: moving forwards
title Graves’ disease: moving forwards
title_full Graves’ disease: moving forwards
title_fullStr Graves’ disease: moving forwards
title_full_unstemmed Graves’ disease: moving forwards
title_short Graves’ disease: moving forwards
title_sort graves’ disease: moving forwards
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086272/
https://www.ncbi.nlm.nih.gov/pubmed/35831126
http://dx.doi.org/10.1136/archdischild-2022-323905
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