Targeting chemoattractant chemokine (C–C motif) ligand 2 derived from astrocytes is a promising therapeutic approach in the treatment of neuromyelitis optica spectrum disorders

INTRODUCTION: Aquaporin-4 immunoglobulin G (AQP4-IgG)-induced astrocytes injury is a key mechanism in the pathogenesis of neuromyelitis spectrum disorder (NMOSD), and although CCL2 is involved, its specific role has not been reported. We aimed to further investigate the role and potential mechanisms...

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Detalles Bibliográficos
Autores principales: Wang, Yupeng, Bian, Jiangping, Yao, Mengyuan, Du, Li, Xu, Yun, Chang, Haoxiao, Cong, Hengri, Wei, Yuzhen, Xu, Wangshu, Wang, Huabing, Zhang, Xinghu, Geng, Xingchao, Yin, Linlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086366/
https://www.ncbi.nlm.nih.gov/pubmed/37056770
http://dx.doi.org/10.3389/fimmu.2023.1144532

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