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Body roundness index is related to the low estimated glomerular filtration rate in Chinese population: A cross-sectional study

BACKGROUND: Kidney disease is related to visceral obesity. As a new indicator of obesity, body roundness index (BRI) has not been fully revealed with kidney disease. This study’s objective is to assess the relationship between estimated glomerular filtration rate (eGFR) and BRI among the Chinese pop...

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Autores principales: Zhang, Yue, Gao, Wenxing, Ren, Rui, Liu, Yang, Li, Binqi, Wang, Anping, Tang, Xulei, Yan, Li, Luo, Zuojie, Qin, Guijun, Chen, Lulu, Wan, Qin, Gao, Zhengnan, Wang, Weiqing, Ning, Guang, Mu, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086436/
https://www.ncbi.nlm.nih.gov/pubmed/37056676
http://dx.doi.org/10.3389/fendo.2023.1148662
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author Zhang, Yue
Gao, Wenxing
Ren, Rui
Liu, Yang
Li, Binqi
Wang, Anping
Tang, Xulei
Yan, Li
Luo, Zuojie
Qin, Guijun
Chen, Lulu
Wan, Qin
Gao, Zhengnan
Wang, Weiqing
Ning, Guang
Mu, Yiming
author_facet Zhang, Yue
Gao, Wenxing
Ren, Rui
Liu, Yang
Li, Binqi
Wang, Anping
Tang, Xulei
Yan, Li
Luo, Zuojie
Qin, Guijun
Chen, Lulu
Wan, Qin
Gao, Zhengnan
Wang, Weiqing
Ning, Guang
Mu, Yiming
author_sort Zhang, Yue
collection PubMed
description BACKGROUND: Kidney disease is related to visceral obesity. As a new indicator of obesity, body roundness index (BRI) has not been fully revealed with kidney disease. This study’s objective is to assess the relationship between estimated glomerular filtration rate (eGFR) and BRI among the Chinese population. METHODS: This study enrolled 36,784 members over the age of 40, they were from 7 centers in China by using a random sampling method. BRI was computed using height and waist circumference, eGFR ≤ 90 mL/min/1.73 m(2) was considered to indicate low eGFR. To lessen bias, propensity score matching was employed, multiple logistic regression models were utilized to examine the connection between low eGFR and BRI. RESULTS: The age, diabetes and coronary heart disease rates, fasting blood glucose, and triglycerides were all greater in participants with low eGFR. The BRI quartile was still positively connected with low eGFR after controlling for confounding variables, according to multivariate logistic regression analysis. (OR [95%CI] Q2:1.052 [1.021-1.091], OR [95%CI] Q3:1.189 [1.062-1.284], OR [95%CI] Q4:1.283 [1.181-1.394], P trend < 0.001). Stratified research revealed that the elders, women, habitual smokers, and those with a history of diabetes or hypertension experienced the connection between BRI level and low eGFR. According to ROC, BRI was able to detect low eGFR more accurately. CONCLUSION: Low eGFR in the Chinese community is positively connected with BRI, which has the potential to be used as an effective indicator for screening kidney disease to identify high-risk groups and take appropriate measures to prevent subsequent complications.
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spelling pubmed-100864362023-04-12 Body roundness index is related to the low estimated glomerular filtration rate in Chinese population: A cross-sectional study Zhang, Yue Gao, Wenxing Ren, Rui Liu, Yang Li, Binqi Wang, Anping Tang, Xulei Yan, Li Luo, Zuojie Qin, Guijun Chen, Lulu Wan, Qin Gao, Zhengnan Wang, Weiqing Ning, Guang Mu, Yiming Front Endocrinol (Lausanne) Endocrinology BACKGROUND: Kidney disease is related to visceral obesity. As a new indicator of obesity, body roundness index (BRI) has not been fully revealed with kidney disease. This study’s objective is to assess the relationship between estimated glomerular filtration rate (eGFR) and BRI among the Chinese population. METHODS: This study enrolled 36,784 members over the age of 40, they were from 7 centers in China by using a random sampling method. BRI was computed using height and waist circumference, eGFR ≤ 90 mL/min/1.73 m(2) was considered to indicate low eGFR. To lessen bias, propensity score matching was employed, multiple logistic regression models were utilized to examine the connection between low eGFR and BRI. RESULTS: The age, diabetes and coronary heart disease rates, fasting blood glucose, and triglycerides were all greater in participants with low eGFR. The BRI quartile was still positively connected with low eGFR after controlling for confounding variables, according to multivariate logistic regression analysis. (OR [95%CI] Q2:1.052 [1.021-1.091], OR [95%CI] Q3:1.189 [1.062-1.284], OR [95%CI] Q4:1.283 [1.181-1.394], P trend < 0.001). Stratified research revealed that the elders, women, habitual smokers, and those with a history of diabetes or hypertension experienced the connection between BRI level and low eGFR. According to ROC, BRI was able to detect low eGFR more accurately. CONCLUSION: Low eGFR in the Chinese community is positively connected with BRI, which has the potential to be used as an effective indicator for screening kidney disease to identify high-risk groups and take appropriate measures to prevent subsequent complications. Frontiers Media S.A. 2023-03-28 /pmc/articles/PMC10086436/ /pubmed/37056676 http://dx.doi.org/10.3389/fendo.2023.1148662 Text en Copyright © 2023 Zhang, Gao, Ren, Liu, Li, Wang, Tang, Yan, Luo, Qin, Chen, Wan, Gao, Wang, Ning and Mu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Zhang, Yue
Gao, Wenxing
Ren, Rui
Liu, Yang
Li, Binqi
Wang, Anping
Tang, Xulei
Yan, Li
Luo, Zuojie
Qin, Guijun
Chen, Lulu
Wan, Qin
Gao, Zhengnan
Wang, Weiqing
Ning, Guang
Mu, Yiming
Body roundness index is related to the low estimated glomerular filtration rate in Chinese population: A cross-sectional study
title Body roundness index is related to the low estimated glomerular filtration rate in Chinese population: A cross-sectional study
title_full Body roundness index is related to the low estimated glomerular filtration rate in Chinese population: A cross-sectional study
title_fullStr Body roundness index is related to the low estimated glomerular filtration rate in Chinese population: A cross-sectional study
title_full_unstemmed Body roundness index is related to the low estimated glomerular filtration rate in Chinese population: A cross-sectional study
title_short Body roundness index is related to the low estimated glomerular filtration rate in Chinese population: A cross-sectional study
title_sort body roundness index is related to the low estimated glomerular filtration rate in chinese population: a cross-sectional study
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086436/
https://www.ncbi.nlm.nih.gov/pubmed/37056676
http://dx.doi.org/10.3389/fendo.2023.1148662
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