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Th2 high and mast cell gene signatures are associated with corticosteroid sensitivity in COPD

RATIONALE: Severe asthma and chronic obstructive pulmonary disease (COPD) share common pathophysiological traits such as relative corticosteroid insensitivity. We recently published three transcriptome-associated clusters (TACs) using hierarchical analysis of the sputum transcriptome in asthmatics f...

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Detalles Bibliográficos
Autores principales:	Faiz, Alen, Pavlidis, Stelios, Kuo, Chih-Hsi, Rowe, Anthony, Hiemstra, Pieter S, Timens, Wim, Berg, Marijn, Wisman, Marissa, Guo, Yi-Ke, Djukanović, Ratko, Sterk, Peter, Meyer, Kerstin B, Nawijn, Martijn C, Adcock, Ian, Chung, Kian Fan, van den Berge, Maarten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Chronic Obstructive Pulmonary Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086461/ https://www.ncbi.nlm.nih.gov/pubmed/36598042 http://dx.doi.org/10.1136/thorax-2021-217736

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