Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy

Cardiomyopathy is a progressive disease of the myocardium leading to impaired contractility. Genotoxic cancer therapies are known to be potent drivers of cardiomyopathy, whereas causes of spontaneous disease remain unclear. To test the hypothesis that endogenous genotoxic stress contributes to cardi...

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Detalles Bibliográficos
Autores principales: Henpita, Chathurika, Vyas, Rajesh, Healy, Chastity L., Kieu, Tra L., Gurkar, Aditi U., Yousefzadeh, Matthew J., Cui, Yuxiang, Lu, Aiping, Angelini, Luise A., O'Kelly, Ryan D., McGowan, Sara J., Chandrasekhar, Sanjay, Vanderpool, Rebecca R., Hennessy‐Wack, Danielle, Ross, Mark A., Bachman, Timothy N., McTiernan, Charles, Pillai, Smitha P. S., Ladiges, Warren, Lavasani, Mitra, Huard, Johnny, Beer‐Stolz, Donna, St. Croix, Claudette M., Watkins, Simon C., Robbins, Paul D., Mora, Ana L., Kelley, Eric E., Wang, Yinsheng, O'Connell, Timothy D., Niedernhofer, Laura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086531/
https://www.ncbi.nlm.nih.gov/pubmed/36734200
http://dx.doi.org/10.1111/acel.13782

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