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Interferon regulates neural stem cell function at all ages by orchestrating mTOR and cell cycle

Stem cells show intrinsic interferon signalling, which protects them from viral infections at all ages. In the ageing brain, interferon signalling also reduces the ability of stem cells to activate. Whether these functions are linked and at what time interferons start taking on a role in stem cell f...

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Detalles Bibliográficos
Autores principales: Carvajal Ibañez, Damian, Skabkin, Maxim, Hooli, Jooa, Cerrizuela, Santiago, Göpferich, Manuel, Jolly, Adrien, Volk, Katrin, Zumwinkel, Marc, Bertolini, Matilde, Figlia, Gianluca, Höfer, Thomas, Kramer, Guenter, Anders, Simon, Teleman, Aurelio A, Marciniak‐Czochra, Anna, Martin‐Villalba, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086582/
https://www.ncbi.nlm.nih.gov/pubmed/36636818
http://dx.doi.org/10.15252/emmm.202216434