Effect of 5’-Fluoro-2’-Deoxycytidine and Sodium Butyrate on the Gene Expression of the Intrinsic Apoptotic Pathway, p21, p27, and p53 Genes Expression, Cell Viability, and Apoptosis in Human Hepatocellular Carcinoma Cell Lines

BACKGROUND: Epigenetic mechanisms play an important role in the regulation of gene expression and genetic information. DNA methyltransferases are a family of enzymes that methylate DNA at the promoter region of the gene which can significantly contribute to gene silencing and carcinogenesis. In addi...

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Detalles Bibliográficos
Autores principales: Sanaei, Masumeh, Kavoosi, Fraidoon, Safari, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086643/
https://www.ncbi.nlm.nih.gov/pubmed/37057236
http://dx.doi.org/10.4103/abr.abr_211_21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086643/
https://www.ncbi.nlm.nih.gov/pubmed/37057236
http://dx.doi.org/10.4103/abr.abr_211_21

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