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Crushing lopinavir/ritonavir tablets does not result in lower exposure to lopinavir/ritonavir in adult patients with COVID-19

OBJECTIVE: Lopinavir/ritonavir (LPV/RTV) exposure is decreased in children after crushing the tablets. Whether exposure is also decreased in adult patients is not known. This study evaluated the exposure of LPV/RTV in adult patients after administration of crushed LPV/RTV tablets. METHODS: Blood sam...

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Detalles Bibliográficos
Autores principales:	Mohsenian Naghani, Shaghayegh, Jansen, Mark MPM, Jaspers, Tessa, Bastiaans, Diane, Burger, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086723/ https://www.ncbi.nlm.nih.gov/pubmed/33990390 http://dx.doi.org/10.1136/ejhpharm-2020-002596

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