Cargando…

Cancer-associated fibroblasts promote migration and invasion of non-small cell lung cancer cells via METTL3-mediated RAC3 m(6)A modification

Cancer progression depends on the communication between tumor cells and tumor microenvironment. Cancer-associated fibroblasts (CAFs) are a major component of stromal cells. CAFs promote cancer metastasis; however, it has not been evaluated whether N6-methyladenosine (m(6)A) modification is responsib...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Mengmeng, Zhang, Qicheng, Zheng, Sijia, Guo, Xueru, Cao, Limin, Ren, Yinghui, Qian, Yongmei, Wang, Min, Wu, Xiang, Xu, Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086740/ https://www.ncbi.nlm.nih.gov/pubmed/37056933 http://dx.doi.org/10.7150/ijbs.79467

Ejemplares similares

Cancer-Associated Fibroblasts Promote Migration and Invasion of Non-Small Cell Lung Cancer Cells via miR-101-3p Mediated VEGFA Secretion and AKT/eNOS Pathway
por: Guo, Xueru, et al.
Publicado: (2021)

Autophagic secretion of HMGB1 from cancer-associated fibroblasts promotes metastatic potential of non-small cell lung cancer cells via NFκB signaling
por: Ren, Yinghui, et al.
Publicado: (2021)

Cancer‐associated fibroblasts contribute to cisplatin resistance by modulating ANXA3 in lung cancer cells
por: Wang, Limin, et al.
Publicado: (2019)

The Metastasis Potential Promoting Capacity of Cancer-Associated Fibroblasts Was Attenuated by Cisplatin via Modulating KRT8
por: Li, Xueqin, et al.
Publicado: (2020)

Cancer-associated fibroblasts enhance metastatic potential of lung cancer cells through IL-6/STAT3 signaling pathway
por: Wang, Limin, et al.
Publicado: (2017)

Hsa-microRNA-101 suppresses migration and invasion by targeting Rac1 in thyroid cancer cells
por: WANG, CHENGHAI, et al.
Publicado: (2014)

METTL3 promotes proliferation and migration of colorectal cancer cells by increasing SNHG1 stability
por: Xu, Yeqiu, et al.
Publicado: (2023)

Silencing of METTL3 effectively hinders invasion and metastasis of prostate cancer cells
por: Chen, Yabing, et al.
Publicado: (2021)

Alternative splicing of METTL3 explains apparently METTL3-independent m(6)A modifications in mRNA
por: Poh, Hui Xian, et al.
Publicado: (2022)

METTL3-IGF2BP3-axis mediates the proliferation and migration of pancreatic cancer by regulating spermine synthase m6A modification
por: Guo, Zhenyun, et al.
Publicado: (2022)

METTL3 Promotes the Proliferation and Mobility of Gastric Cancer Cells
por: Lin, Sen, et al.
Publicado: (2019)

A cleaved METTL3 potentiates the METTL3–WTAP interaction and breast cancer progression
por: Yan, Chaojun, et al.
Publicado: (2023)

Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells
por: Baugher, Paige J, et al.
Publicado: (2005)

METTL3-mediated m(6)A modification of TIMP2 mRNA promotes podocyte injury in diabetic nephropathy
por: Jiang, Ling, et al.
Publicado: (2022)

Rac1 and Rac3 GTPases Regulate the Development of Hilar Mossy Cells by Affecting the Migration of Their Precursors to the Hilus
por: Pennucci, Roberta, et al.
Publicado: (2011)

METTL3-dependent m(6)A modification programs T follicular helper cell differentiation
por: Yao, Yingpeng, et al.
Publicado: (2021)

Analysis of METTL3 and METTL14 in hepatocellular carcinoma
por: Liu, Xiangxiang, et al.
Publicado: (2020)

The Comprehensive Analysis of N6-Methyadenosine Writer METTL3 and METTL14 in Gastric Cancer
por: Ge, Yiling, et al.
Publicado: (2023)

METTL13 is downregulated in bladder carcinoma and suppresses cell proliferation, migration and invasion
por: Zhang, Zhe, et al.
Publicado: (2016)

The Distinct Function and Localization of METTL3/METTL14 and METTL16 Enzymes in Cardiomyocytes
por: Arcidiacono, Orazio Angelo, et al.
Publicado: (2020)

METTL3 promotes chemoresistance in small cell lung cancer by inducing mitophagy
por: Sun, Yueqin, et al.
Publicado: (2023)

METTL3-Dependent N6-Methyladenosine Modification Programs Human Neural Progenitor Cell Proliferation
por: Zhao, Yuan, et al.
Publicado: (2023)

Two Rac1 pools integrate the direction and coordination of collective cell migration
por: Zhou, Sijia, et al.
Publicado: (2022)

DARS-AS1 recruits METTL3/METTL14 to bind and enhance DARS mRNA m(6)A modification and translation for cytoprotective autophagy in cervical cancer
por: Zhu, Miaohua, et al.
Publicado: (2022)

Roles of METTL3 in cancer: mechanisms and therapeutic targeting
por: Zeng, Chengwu, et al.
Publicado: (2020)

Critical Roles of METTL3 in Translation Regulation of Cancer
por: Meng, Wangyang, et al.
Publicado: (2023)

Expression and clinical significance of METTL3 in colorectal cancer
por: Li, Hui, et al.
Publicado: (2023)

METTL3-mediated m(6)A modification is required for cerebellar development
por: Wang, Chen-Xin, et al.
Publicado: (2018)

N (6)-methyladenosine modification and METTL3 modulate enterovirus 71 replication
por: Hao, Haojie, et al.
Publicado: (2019)

METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer
por: Yue, Ben, et al.
Publicado: (2019)

METTL3 Accelerates Breast Cancer Progression via Regulating EZH2 m(6)A Modification
por: Hu, Shaojun, et al.
Publicado: (2022)

Fusobacterium nucleatum reduces METTL3-mediated m(6)A modification and contributes to colorectal cancer metastasis
por: Chen,, Shujie, et al.
Publicado: (2022)

RAC3 Promotes Proliferation, Migration and Invasion via PYCR1/JAK/STAT Signaling in Bladder Cancer
por: Cheng, Chuanyu, et al.
Publicado: (2020)

Deficiency of Mettl3 in Bladder Cancer Stem Cells Inhibits Bladder Cancer Progression and Angiogenesis
por: Wang, Ganping, et al.
Publicado: (2021)

METTL3-mediated m(6)A modification regulates cell cycle progression of dental pulp stem cells
por: Luo, Haiyun, et al.
Publicado: (2021)

METTL3 suppresses anlotinib sensitivity by regulating m(6)A modification of FGFR3 in oral squamous cell carcinoma
por: Chen, Jie, et al.
Publicado: (2022)

bFGF Regulates PI3-Kinase-Rac1-JNK Pathway and Promotes Fibroblast Migration in Wound Healing
por: Kanazawa, Shigeyuki, et al.
Publicado: (2010)

The feedback loop of METTL14 and USP38 regulates cell migration, invasion and EMT as well as metastasis in bladder cancer
por: Huang, Ji, et al.
Publicado: (2022)

Rac Activation by the T-Cell Receptor Inhibits T Cell Migration
por: Cernuda-Morollón, Eva, et al.
Publicado: (2010)

Rac3 Regulates Cell Invasion, Migration and EMT in Lung Adenocarcinoma through p38 MAPK Pathway
por: Zhang, Chenlei, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ti3aiueug9jfdq8n2c3i3e5lfk