Parkin increases the risk of colitis by downregulation of VDR via autophagy-lysosome degradation

Parkin, an E3 ubiquitin ligase, plays an essential role in mitophagy. Emerging evidence indicates that mitophagy is involved in various processes closely related to immune diseases, including inflammatory bowel diseases (IBD). Here, the authors show that Parkin increases the occurrence of colitis an...

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Detalles Bibliográficos
Autores principales: Ma, Zemeng, Wu, Junxian, Wu, Yuqing, Sun, Xiaomeng, Rao, Zebing, Sun, Naishuang, Fu, Yu, Zhang, Zaikui, Li, Jingzhou, Xiao, Mengjun, Zeng, Qiang, Wu, Yuxuan, Han, Chenhua, Ding, Ding, Zhang, Hongjie, Yuan, Hua, zhang, Jing, Yang, Shuo, Chen, Yunzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086757/
https://www.ncbi.nlm.nih.gov/pubmed/37056928
http://dx.doi.org/10.7150/ijbs.77153

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