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Global colorectal cancer research, 2007‐2021: Outputs and funding

The purpose of this study was to provide an evidence base for colorectal cancer research activity that might influence policy, mainly at the national level. Improvements in healthcare delivery have lengthened life expectancy, but within a situation of increased cancer incidence. The disease burden o...

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Autores principales: Begum, Mursheda, Lewison, Grant, Wang, Xiang, Dunne, Philip D., Maughan, Tim, Sullivan, Richard, Lawler, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086800/
https://www.ncbi.nlm.nih.gov/pubmed/36082449
http://dx.doi.org/10.1002/ijc.34279
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author Begum, Mursheda
Lewison, Grant
Wang, Xiang
Dunne, Philip D.
Maughan, Tim
Sullivan, Richard
Lawler, Mark
author_facet Begum, Mursheda
Lewison, Grant
Wang, Xiang
Dunne, Philip D.
Maughan, Tim
Sullivan, Richard
Lawler, Mark
author_sort Begum, Mursheda
collection PubMed
description The purpose of this study was to provide an evidence base for colorectal cancer research activity that might influence policy, mainly at the national level. Improvements in healthcare delivery have lengthened life expectancy, but within a situation of increased cancer incidence. The disease burden of CRC has risen significantly, particularly in Africa, Asia and Latin America. Research is key to its control and reduction, but few studies have delineated the volume and funding of global research on CRC. We identified research papers in the Web of Science (WoS) from 2007 to 2021, and determined the contributions of the leading countries, the research domains studied, and their sources of funding. We identified 62 716 papers, representing 5.7% of all cancer papers. This percentage was somewhat disproportionate to the disease burden (7.7% in 2015), especially in Eastern Europe. International collaboration increased over the time period in almost all countries except in China. Genetics, surgery and prognosis were the leading research domains. However, research on palliative care and quality‐of‐life in CRC was lacking. In Western Europe, the main funding source was the charity sector, particularly in the UK, but in most other countries government played the leading role, especially in China and the USA. There was little support from industry. Several Asian countries provided minimal contestable funding, which may have reduced the impact of their CRC research. Certain countries must perform more CRC research overall, especially in domains such as screening, palliative care and quality‐of‐life. The private‐non‐profit sector should be an alternative source of support.
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spelling pubmed-100868002023-04-12 Global colorectal cancer research, 2007‐2021: Outputs and funding Begum, Mursheda Lewison, Grant Wang, Xiang Dunne, Philip D. Maughan, Tim Sullivan, Richard Lawler, Mark Int J Cancer Cancer Therapy and Prevention The purpose of this study was to provide an evidence base for colorectal cancer research activity that might influence policy, mainly at the national level. Improvements in healthcare delivery have lengthened life expectancy, but within a situation of increased cancer incidence. The disease burden of CRC has risen significantly, particularly in Africa, Asia and Latin America. Research is key to its control and reduction, but few studies have delineated the volume and funding of global research on CRC. We identified research papers in the Web of Science (WoS) from 2007 to 2021, and determined the contributions of the leading countries, the research domains studied, and their sources of funding. We identified 62 716 papers, representing 5.7% of all cancer papers. This percentage was somewhat disproportionate to the disease burden (7.7% in 2015), especially in Eastern Europe. International collaboration increased over the time period in almost all countries except in China. Genetics, surgery and prognosis were the leading research domains. However, research on palliative care and quality‐of‐life in CRC was lacking. In Western Europe, the main funding source was the charity sector, particularly in the UK, but in most other countries government played the leading role, especially in China and the USA. There was little support from industry. Several Asian countries provided minimal contestable funding, which may have reduced the impact of their CRC research. Certain countries must perform more CRC research overall, especially in domains such as screening, palliative care and quality‐of‐life. The private‐non‐profit sector should be an alternative source of support. John Wiley & Sons, Inc. 2022-09-28 2023-02-01 /pmc/articles/PMC10086800/ /pubmed/36082449 http://dx.doi.org/10.1002/ijc.34279 Text en © 2022 The Authors. International Journal of Cancer published by John Wiley & Sons Ltd on behalf of UICC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cancer Therapy and Prevention
Begum, Mursheda
Lewison, Grant
Wang, Xiang
Dunne, Philip D.
Maughan, Tim
Sullivan, Richard
Lawler, Mark
Global colorectal cancer research, 2007‐2021: Outputs and funding
title Global colorectal cancer research, 2007‐2021: Outputs and funding
title_full Global colorectal cancer research, 2007‐2021: Outputs and funding
title_fullStr Global colorectal cancer research, 2007‐2021: Outputs and funding
title_full_unstemmed Global colorectal cancer research, 2007‐2021: Outputs and funding
title_short Global colorectal cancer research, 2007‐2021: Outputs and funding
title_sort global colorectal cancer research, 2007‐2021: outputs and funding
topic Cancer Therapy and Prevention
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10086800/
https://www.ncbi.nlm.nih.gov/pubmed/36082449
http://dx.doi.org/10.1002/ijc.34279
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