Physiologically‐based pharmacokinetic model to investigate the effect of pregnancy on risperidone and paliperidone pharmacokinetics: Application to a pregnant woman and her neonate

This study aimed to determine the effects of pregnancy and ontogeny on risperidone and paliperidone pharmacokinetics by assessing their serum concentrations in two subjects and constructing a customized physiologically‐based pharmacokinetic (PBPK) model. Risperidone and paliperidone serum concentrat...

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Detalles Bibliográficos
Autores principales: Mahdy, Walaa Y. B., Yamamoto, Kazuhiro, Ito, Takahiro, Fujiwara, Naoko, Fujioka, Kazumichi, Horai, Tadasu, Otsuka, Ikuo, Imafuku, Hitomi, Omura, Tomohiro, Iijima, Kazumoto, Yano, Ikuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087078/
https://www.ncbi.nlm.nih.gov/pubmed/36655374
http://dx.doi.org/10.1111/cts.13473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087078/
https://www.ncbi.nlm.nih.gov/pubmed/36655374
http://dx.doi.org/10.1111/cts.13473

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