Rapid and precise genotyping of transgene zygosity in mice using an allele-specific method

Precise determination of transgene zygosity is essential for use of transgenic mice in research. Because integration loci of transgenes are usually unknown due to their random insertion, assessment of transgene zygosity remains a challenge. Current zygosity genotyping methods (progeny testing, qPCR,...

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Detalles Bibliográficos
Autores principales: Yang, Jianqi, DeVore, Alison N, Fu, Daniel A, Spicer, Mackenzie M, Guo, Mengcheng, Thompson, Samantha G, Ahlers-Dannen, Katelin E, Polato, Federica, Nussenzweig, Andre, Fisher, Rory A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087101/
https://www.ncbi.nlm.nih.gov/pubmed/37037594
http://dx.doi.org/10.26508/lsa.202201729

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