Cargando…

Rapid pruritus reduction with ruxolitinib cream treatment in patients with atopic dermatitis

BACKGROUND: Ruxolitinib cream is a topical formulation of ruxolitinib, a Janus kinase (JAK) 1/JAK2 inhibitor. OBJECTIVES: To report timing and magnitude of effect of ruxolitinib cream on itch in patients with atopic dermatitis (AD), a highly pruritic inflammatory skin disease. METHODS: Two phase 3 t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Blauvelt, Andrew, Kircik, Leon, Papp, Kim A., Simpson, Eric L., Silverberg, Jonathan I., Kim, Brian S., Kwatra, Shawn G., Kuligowski, Michael E., Venturanza, May E., Wei, Shaoceng, Szepietowski, Jacek C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles and Short Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087253/ https://www.ncbi.nlm.nih.gov/pubmed/36066323 http://dx.doi.org/10.1111/jdv.18571

Ejemplares similares

Pharmacokinetics of Ruxolitinib in Patients with Atopic Dermatitis Treated With Ruxolitinib Cream: Data from Phase II and III Studies
por: Gong, Xiaohua, et al.
Publicado: (2021)

Ruxolitinib Cream Has Dual Efficacy on Pruritus and Inflammation in Experimental Dermatitis
por: Scuron, Monika D., et al.
Publicado: (2021)

A Maximum-Use Trial of Ruxolitinib Cream in Adolescents and Adults with Atopic Dermatitis
por: Bissonnette, Robert, et al.
Publicado: (2022)

Ruxolitinib Cream 1.5%: A Review in Mild to Moderate Atopic Dermatitis
por: Hoy, Sheridan M.
Publicado: (2022)

Correction to: Ruxolitinib Cream 1.5%: A Review in Mild to Moderate Atopic Dermatitis
por: Hoy, Sheridan M.
Publicado: (2023)

Management of Atopic Dermatitis: Clinical Utility of Ruxolitinib
por: Owji, Shayan, et al.
Publicado: (2022)

Impact of Ruxolitinib Cream on Work Productivity and Activity Impairment and Associated Indirect Costs in Patients with Atopic Dermatitis: Pooled Results From Two Phase III Studies
por: Bloudek, Lisa, et al.
Publicado: (2022)

Neuroimmunological Mechanism of Pruritus in Atopic Dermatitis Focused on the Role of Serotonin
por: Kim, Kwangmi
Publicado: (2012)

Pruritus Associated with Commonly Prescribed Medications in a Tertiary Care Center
por: Huang, Amy H., et al.
Publicado: (2019)

Emerging Methods to Objectively Assess Pruritus in Atopic Dermatitis
por: Smith, Mary Patricia, et al.
Publicado: (2019)

Translational Relevance of Mouse Models of Atopic Dermatitis
por: Choi, Justin, et al.
Publicado: (2021)

Determining Severity Strata for Three Atopic Dermatitis Patient-Reported Outcome Questionnaires: Defining Severity Score Ranges for the Worst Pruritus Numerical Rating Scale and the Atopic Dermatitis Symptom and Impact Scales (ADerm-SS and ADerm-IS)
por: Silverberg, Jonathan I., et al.
Publicado: (2022)

The etiopathogenesis of atopic dermatitis: barrier disruption, immunological derangement, and pruritus
por: Rerknimitr, Pawinee, et al.
Publicado: (2017)

Ruxolitinib cream for the treatment of cutaneous sarcoidosis
por: Smith, Jeffrey S., et al.
Publicado: (2023)

Mediators of Pruritus in Psoriasis
por: Reich, Adam, et al.
Publicado: (2007)

Atopic Dermatitis: Sailing beyond the Sunset with a Multitude of Novel Treatments
por: Gregoriou, Stamatios, et al.
Publicado: (2022)

Neurogenic markers of the inflammatory process in atopic dermatitis: relation to the severity and pruritus
por: Teresiak-Mikołajczak, Ewa, et al.
Publicado: (2013)

Transcutaneous Slowly Depolarizing Currents Elicit Pruritus in Patients with Atopic Dermatitis
por: RUKWIED, Roman, et al.
Publicado: (2020)

Pathomechanism of Pruritus in Psoriasis and Atopic Dermatitis: Novel Approaches, Similarities and Differences
por: Kaczmarska, Agnieszka, et al.
Publicado: (2023)

Treatment of cutaneous lupus with topical ruxolitinib cream
por: Park, Jonathan J., et al.
Publicado: (2022)

Adipokines as Biomarkers of Atopic Dermatitis in Adults
por: Jaworek, Andrzej Kazimierz, et al.
Publicado: (2020)

Relationship Among Treatment, Pruritus, Investigator’s Static Global Assessment, and Quality of Life in Patients with Atopic Dermatitis
por: Simpson, Eric L., et al.
Publicado: (2021)

Efficacy of Heparinoid Cream Containing Pseudo-Ceramide for Remission of Atopic Dermatitis
por: Matsuoka, Megumi, et al.
Publicado: (2021)

Antihistamines in the treatment of pruritus in psoriasis
por: Domagała, Anna, et al.
Publicado: (2017)

Establishment of an Intradermal Canine IL-31-Induced Pruritus Model to Evaluate Therapeutic Candidates in Atopic Dermatitis
por: Pearson, Jason, et al.
Publicado: (2023)

Aprepitant for the Treatment of Chronic Refractory Pruritus
por: He, Alice, et al.
Publicado: (2017)

Improvement in disease severity and pruritus outcomes with crisaborole ointment, 2%, by baseline atopic dermatitis severity in children and adolescents with mild‐to‐moderate atopic dermatitis
por: Eichenfield, Lawrence F., et al.
Publicado: (2020)

Melatonin and sleep disorders in patients with severe atopic dermatitis
por: Jaworek, Andrzej K., et al.
Publicado: (2020)

Pruritus Vulvæ Treated by Acid Stilbœstrol Cream
Publicado: (1942)

Formaldehyde-Induced Aggravation of Pruritus and Dermatitis Is Associated with the Elevated Expression of Th1 Cytokines in a Rat Model of Atopic Dermatitis
por: Han, Rafael Taeho, et al.
Publicado: (2016)

Molecular and cellular mechanisms of itch and pain in atopic dermatitis and implications for novel therapeutics
por: Kwatra, Shawn G, et al.
Publicado: (2022)

The Suppressive Effect of Mamiran Cream on Atopic Dermatitis-Like Skin Lesions In Vivo
por: Aierken, Kailibinuer, et al.
Publicado: (2021)

Assessment of Efficacy and Safety Outcomes Beyond Week 16 in Clinical Trials of Systemic Agents Used for the Treatment of Moderate to Severe Atopic Dermatitis in Combination with Topical Corticosteroids
por: Silverberg, Jonathan I., et al.
Publicado: (2023)

Emerging Therapeutic Options for Chronic Pruritus
por: Reszke, Radomir, et al.
Publicado: (2020)

Associations between atopic dermatitis and other disorders
por: Silverberg, Jonathan I.
Publicado: (2018)

The Anti-Inflammatory and Anti-Pruritus Mechanisms of Huanglian Jiedu Decoction in the Treatment of Atopic Dermatitis
por: Xu, Yubin, et al.
Publicado: (2021)

Effect of Resveratrol-Enriched Rice on Skin Inflammation and Pruritus in the NC/Nga Mouse Model of Atopic Dermatitis
por: Kang, Min Cheol, et al.
Publicado: (2019)

Mirtazapine for the Treatment of Chronic Pruritus
por: Khanna, Raveena, et al.
Publicado: (2019)

Pruritus in pediatric patients with atopic dermatitis: a multidisciplinary approach - summary document from an Italian expert group
por: El Hachem, May, et al.
Publicado: (2020)

Phenotypic differences of atopic dermatitis stratified by age
por: Chatrath, Sheena, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rp5508fuoub4v0pf9kmb7l6fu0