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NR1H3 (LXRα) is associated with pro‐inflammatory macrophages, predicts survival and suggests potential therapeutic rationales in diffuse large b‐cell lymphoma

The role of macrophages (Mo) and their prognostic impact in diffuse large B‐cell lymphomas (DLBCL) remain controversial. By regulating the lipid metabolism, Liver‐X‐Receptors (LXRs) control Mo polarization/inflammatory response, and their pharmacological modulation is under clinical investigation to...

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Detalles Bibliográficos
Autores principales: Vegliante, Maria Carmela, Mazzara, Saveria, Zaccaria, Gian Maria, De Summa, Simona, Esposito, Flavia, Melle, Federica, Motta, Giovanna, Sapienza, Maria Rosaria, Opinto, Giuseppina, Volpe, Giacomo, Bucci, Antonella, Gargano, Grazia, Enjuanes, Anna, Tabanelli, Valentina, Fiori, Stefano, Minoia, Carla, Clemente, Felice, Negri, Antonio, Gulino, Alessandro, Morello, Gaia, Scattone, Anna, Zito, Alfredo F., Tommasi, Stefania, Agostinelli, Claudio, Vitolo, Umberto, Chiappella, Annalisa, Barbui, Anna Maria, Derenzini, Enrico, Zinzani, Pier Luigi, Casadei, Beatrice, Rivas‐Delgado, Alfredo, López‐Guillermo, Armando, Campo, Elias, Moschetta, Antonio, Guarini, Attilio, Pileri, Stefano A., Ciavarella, Sabino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087298/
https://www.ncbi.nlm.nih.gov/pubmed/35850118
http://dx.doi.org/10.1002/hon.3050