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Windows of Vulnerability: Consequences of Exposure Timing during the Dutch Hunger Winter

Prior research on early‐life exposures to famine has established in utero development as a critical period of vulnerability to malnutrition. Yet, previous research tends to focus narrowly on this stage, at the expense of a more comprehensive examination of childhood. As a result, the literature has...

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Autores principales: Ramirez, Daniel, Haas, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087479/
https://www.ncbi.nlm.nih.gov/pubmed/37063488
http://dx.doi.org/10.1111/padr.12513
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author Ramirez, Daniel
Haas, Steven A.
author_facet Ramirez, Daniel
Haas, Steven A.
author_sort Ramirez, Daniel
collection PubMed
description Prior research on early‐life exposures to famine has established in utero development as a critical period of vulnerability to malnutrition. Yet, previous research tends to focus narrowly on this stage, at the expense of a more comprehensive examination of childhood. As a result, the literature has yet to compare the severity of the consequences of exposure to malnutrition across developmentally salient periods. Such comparison is crucial not only in the magnitude of effects but also in the nature of outcomes. Using a restricted population registry‐linked health survey, this study examines the Dutch Hunger Winter to provide a comprehensive examination of the long‐term consequences of in utero, infant, childhood, and adolescent exposure to famine. The results show malnutrition leads to heterogeneous effects depending on when the exposure occurs. In utero exposure to malnutrition leads to deleterious conditions in physical health and lower socioeconomic attainment. For older cohorts, results suggest a resilience to the effects of malnutrition on physical health in late life, but a higher vulnerability to socioeconomic stunting. Furthermore, the results suggest important gender differences in the long‐term impact of malnutrition. Males consistently show stronger negative consequences across a wider array of conditions.
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spelling pubmed-100874792023-04-12 Windows of Vulnerability: Consequences of Exposure Timing during the Dutch Hunger Winter Ramirez, Daniel Haas, Steven A. Popul Dev Rev Articles Prior research on early‐life exposures to famine has established in utero development as a critical period of vulnerability to malnutrition. Yet, previous research tends to focus narrowly on this stage, at the expense of a more comprehensive examination of childhood. As a result, the literature has yet to compare the severity of the consequences of exposure to malnutrition across developmentally salient periods. Such comparison is crucial not only in the magnitude of effects but also in the nature of outcomes. Using a restricted population registry‐linked health survey, this study examines the Dutch Hunger Winter to provide a comprehensive examination of the long‐term consequences of in utero, infant, childhood, and adolescent exposure to famine. The results show malnutrition leads to heterogeneous effects depending on when the exposure occurs. In utero exposure to malnutrition leads to deleterious conditions in physical health and lower socioeconomic attainment. For older cohorts, results suggest a resilience to the effects of malnutrition on physical health in late life, but a higher vulnerability to socioeconomic stunting. Furthermore, the results suggest important gender differences in the long‐term impact of malnutrition. Males consistently show stronger negative consequences across a wider array of conditions. John Wiley and Sons Inc. 2022-09-14 2022-12 /pmc/articles/PMC10087479/ /pubmed/37063488 http://dx.doi.org/10.1111/padr.12513 Text en © 2022 The Authors. Population and Development Review published by Wiley Periodicals LLC on behalf of Population Council. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Articles
Ramirez, Daniel
Haas, Steven A.
Windows of Vulnerability: Consequences of Exposure Timing during the Dutch Hunger Winter
title Windows of Vulnerability: Consequences of Exposure Timing during the Dutch Hunger Winter
title_full Windows of Vulnerability: Consequences of Exposure Timing during the Dutch Hunger Winter
title_fullStr Windows of Vulnerability: Consequences of Exposure Timing during the Dutch Hunger Winter
title_full_unstemmed Windows of Vulnerability: Consequences of Exposure Timing during the Dutch Hunger Winter
title_short Windows of Vulnerability: Consequences of Exposure Timing during the Dutch Hunger Winter
title_sort windows of vulnerability: consequences of exposure timing during the dutch hunger winter
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087479/
https://www.ncbi.nlm.nih.gov/pubmed/37063488
http://dx.doi.org/10.1111/padr.12513
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