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The transdermal cream of Formestane anti-breast cancer by controlling PI3K-Akt pathway and the tumor immune microenvironment

BACKGROUND: Treatment of ER(+) breast cancer with intramuscular formulation of Formestane (4-OHA) shrinks the tumor within weeks. Since the tedious way of intramuscular administration and side effects are not suited for adjuvant treatment, Formestane was withdrawn from the market. A new transdermal...

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Detalles Bibliográficos
Autores principales:	Gao, Lanyang, Zhu, Lei, Shen, Chen, Hou, Xiaoming, Chen, Youyou, Zou, Linglin, Qiang, Huiyan, Teichmann, Alexander T., Fu, Wenguang, Luo, Yao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087521/ https://www.ncbi.nlm.nih.gov/pubmed/37056757 http://dx.doi.org/10.3389/fimmu.2023.1041525

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