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Polymeric Membranes of Chitosan/Aloe Vera Gel Fabrication With Enhanced Swelling and Antimicrobial Properties for Biomedical Applications
Since ancient times, medicinal plants have been used as traditional medicine to treat a variety of ailments. Aloe vera (AV) gel’s therapeutic potential is one of the most effective approach in the fabrication of functional materials. The current study aimed to prepare the AV and chitosan (CS) membra...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087668/ https://www.ncbi.nlm.nih.gov/pubmed/37056472 http://dx.doi.org/10.1177/15593258231169387 |
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author | Iqbal, Dure N. Munir, Atira Abbas, Mazhar Nazir, Arif Ali, Zahid Alshawwa, Samar Z. Iqbal, Munawar Ahmad, Naveed |
author_facet | Iqbal, Dure N. Munir, Atira Abbas, Mazhar Nazir, Arif Ali, Zahid Alshawwa, Samar Z. Iqbal, Munawar Ahmad, Naveed |
author_sort | Iqbal, Dure N. |
collection | PubMed |
description | Since ancient times, medicinal plants have been used as traditional medicine to treat a variety of ailments. Aloe vera (AV) gel’s therapeutic potential is one of the most effective approach in the fabrication of functional materials. The current study aimed to prepare the AV and chitosan (CS) membranes using various cross-linkers that were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform-infrared (FT-IR) spectroscopy, thermal gravimetric analysis (TGA), and ultraviolet-visible (UV-Visible) techniques, as well as swelling ratio and antimicrobial studies. SEM analysis revealed that the membrane is porous, with interconnected pores. The inclusion of AV contents in the membrane improved thermal stability and crystallinity. The swelling ratio of the ACPG-3 membrane with a 2:1 CS to AV ratio was 366%. The membranes showed promising antimicrobial activity against Escherichia coli, Staphylococcus aureus, Bacillus subtilis, and Pasteurella multocida strains. The findings revealed that polymeric CS/AV membranes have effective potential for use in the biomedical field. |
format | Online Article Text |
id | pubmed-10087668 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-100876682023-04-12 Polymeric Membranes of Chitosan/Aloe Vera Gel Fabrication With Enhanced Swelling and Antimicrobial Properties for Biomedical Applications Iqbal, Dure N. Munir, Atira Abbas, Mazhar Nazir, Arif Ali, Zahid Alshawwa, Samar Z. Iqbal, Munawar Ahmad, Naveed Dose Response Original Article Since ancient times, medicinal plants have been used as traditional medicine to treat a variety of ailments. Aloe vera (AV) gel’s therapeutic potential is one of the most effective approach in the fabrication of functional materials. The current study aimed to prepare the AV and chitosan (CS) membranes using various cross-linkers that were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform-infrared (FT-IR) spectroscopy, thermal gravimetric analysis (TGA), and ultraviolet-visible (UV-Visible) techniques, as well as swelling ratio and antimicrobial studies. SEM analysis revealed that the membrane is porous, with interconnected pores. The inclusion of AV contents in the membrane improved thermal stability and crystallinity. The swelling ratio of the ACPG-3 membrane with a 2:1 CS to AV ratio was 366%. The membranes showed promising antimicrobial activity against Escherichia coli, Staphylococcus aureus, Bacillus subtilis, and Pasteurella multocida strains. The findings revealed that polymeric CS/AV membranes have effective potential for use in the biomedical field. SAGE Publications 2023-04-07 /pmc/articles/PMC10087668/ /pubmed/37056472 http://dx.doi.org/10.1177/15593258231169387 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Article Iqbal, Dure N. Munir, Atira Abbas, Mazhar Nazir, Arif Ali, Zahid Alshawwa, Samar Z. Iqbal, Munawar Ahmad, Naveed Polymeric Membranes of Chitosan/Aloe Vera Gel Fabrication With Enhanced Swelling and Antimicrobial Properties for Biomedical Applications |
title | Polymeric Membranes of Chitosan/Aloe Vera Gel Fabrication With
Enhanced Swelling and Antimicrobial Properties for Biomedical
Applications |
title_full | Polymeric Membranes of Chitosan/Aloe Vera Gel Fabrication With
Enhanced Swelling and Antimicrobial Properties for Biomedical
Applications |
title_fullStr | Polymeric Membranes of Chitosan/Aloe Vera Gel Fabrication With
Enhanced Swelling and Antimicrobial Properties for Biomedical
Applications |
title_full_unstemmed | Polymeric Membranes of Chitosan/Aloe Vera Gel Fabrication With
Enhanced Swelling and Antimicrobial Properties for Biomedical
Applications |
title_short | Polymeric Membranes of Chitosan/Aloe Vera Gel Fabrication With
Enhanced Swelling and Antimicrobial Properties for Biomedical
Applications |
title_sort | polymeric membranes of chitosan/aloe vera gel fabrication with
enhanced swelling and antimicrobial properties for biomedical
applications |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087668/ https://www.ncbi.nlm.nih.gov/pubmed/37056472 http://dx.doi.org/10.1177/15593258231169387 |
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