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Hospital pharmacists' opinions on a risk prediction tool for medication‐related harm in older people

AIM: Older adults are particularly affected by medication‐related harm (MRH) during transitions of care. There are no clinical tools predicting those at highest risk of MRH post hospital discharge. The PRIME study (prospective study to develop a model to stratify the risk of MRH in hospitalized pati...

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Autores principales: Hussain, Ahmed, Ali, Khalid, Davies, J. Graham, Stevenson, Jennifer M., Lippett, Samantha, O'Malley, Mairead, Parekh, Nikesh, Rajkumar, Chakravarthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087672/
https://www.ncbi.nlm.nih.gov/pubmed/35986928
http://dx.doi.org/10.1111/bcp.15502
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author Hussain, Ahmed
Ali, Khalid
Davies, J. Graham
Stevenson, Jennifer M.
Lippett, Samantha
O'Malley, Mairead
Parekh, Nikesh
Rajkumar, Chakravarthi
author_facet Hussain, Ahmed
Ali, Khalid
Davies, J. Graham
Stevenson, Jennifer M.
Lippett, Samantha
O'Malley, Mairead
Parekh, Nikesh
Rajkumar, Chakravarthi
author_sort Hussain, Ahmed
collection PubMed
description AIM: Older adults are particularly affected by medication‐related harm (MRH) during transitions of care. There are no clinical tools predicting those at highest risk of MRH post hospital discharge. The PRIME study (prospective study to develop a model to stratify the risk of MRH in hospitalized patients) developed and internally validated a risk‐prediction tool (RPT) that provides a percentage score of MRH in adults over 65 in the 8 weeks following hospital discharge. This qualitative study aimed to explore the views of hospital pharmacists around enablers and barriers to clinical implementation of the PRIME‐RPT. METHODS: Ten hospital pharmacists: (band 6, n = 3; band 7, n = 2; band 8, n = 5) participated in semistructured interviews at the Royal Sussex County Hospital (Brighton, UK). The pharmacists were presented with five case‐vignettes each with a calculated PRIME‐RPT score to help guide discussion. Case‐vignettes were designed to be representative of common clinical encounters. Data were thematically analysed using a “framework” approach. RESULTS: Seven themes emerged in relation to the PRIME‐RPT: (1) providing a medicine‐prioritisation aide; (2) acting as a deprescribing alert; (3) facilitating a holistic review of patient medication management; (4) simplifying communication of MRH to patients and the multidisciplinary team; (5) streamlining community follow‐up and integration of risk discussion into clinical practice; (6) identifying barriers for the RPTs integration in clinical practice; and (7) acknowledging its limitations. CONCLUSION: Hospital pharmacists found the PRIME‐RPT beneficial in identifying older patients at high risk of MRH following hospital discharge, facilitating prioritising interventions to those at highest risk while still acknowledging its limitations.
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spelling pubmed-100876722023-04-12 Hospital pharmacists' opinions on a risk prediction tool for medication‐related harm in older people Hussain, Ahmed Ali, Khalid Davies, J. Graham Stevenson, Jennifer M. Lippett, Samantha O'Malley, Mairead Parekh, Nikesh Rajkumar, Chakravarthi Br J Clin Pharmacol Original Articles AIM: Older adults are particularly affected by medication‐related harm (MRH) during transitions of care. There are no clinical tools predicting those at highest risk of MRH post hospital discharge. The PRIME study (prospective study to develop a model to stratify the risk of MRH in hospitalized patients) developed and internally validated a risk‐prediction tool (RPT) that provides a percentage score of MRH in adults over 65 in the 8 weeks following hospital discharge. This qualitative study aimed to explore the views of hospital pharmacists around enablers and barriers to clinical implementation of the PRIME‐RPT. METHODS: Ten hospital pharmacists: (band 6, n = 3; band 7, n = 2; band 8, n = 5) participated in semistructured interviews at the Royal Sussex County Hospital (Brighton, UK). The pharmacists were presented with five case‐vignettes each with a calculated PRIME‐RPT score to help guide discussion. Case‐vignettes were designed to be representative of common clinical encounters. Data were thematically analysed using a “framework” approach. RESULTS: Seven themes emerged in relation to the PRIME‐RPT: (1) providing a medicine‐prioritisation aide; (2) acting as a deprescribing alert; (3) facilitating a holistic review of patient medication management; (4) simplifying communication of MRH to patients and the multidisciplinary team; (5) streamlining community follow‐up and integration of risk discussion into clinical practice; (6) identifying barriers for the RPTs integration in clinical practice; and (7) acknowledging its limitations. CONCLUSION: Hospital pharmacists found the PRIME‐RPT beneficial in identifying older patients at high risk of MRH following hospital discharge, facilitating prioritising interventions to those at highest risk while still acknowledging its limitations. John Wiley and Sons Inc. 2022-09-15 2023-02 /pmc/articles/PMC10087672/ /pubmed/35986928 http://dx.doi.org/10.1111/bcp.15502 Text en © 2022 The Authors. British Journal of Clinical Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Hussain, Ahmed
Ali, Khalid
Davies, J. Graham
Stevenson, Jennifer M.
Lippett, Samantha
O'Malley, Mairead
Parekh, Nikesh
Rajkumar, Chakravarthi
Hospital pharmacists' opinions on a risk prediction tool for medication‐related harm in older people
title Hospital pharmacists' opinions on a risk prediction tool for medication‐related harm in older people
title_full Hospital pharmacists' opinions on a risk prediction tool for medication‐related harm in older people
title_fullStr Hospital pharmacists' opinions on a risk prediction tool for medication‐related harm in older people
title_full_unstemmed Hospital pharmacists' opinions on a risk prediction tool for medication‐related harm in older people
title_short Hospital pharmacists' opinions on a risk prediction tool for medication‐related harm in older people
title_sort hospital pharmacists' opinions on a risk prediction tool for medication‐related harm in older people
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087672/
https://www.ncbi.nlm.nih.gov/pubmed/35986928
http://dx.doi.org/10.1111/bcp.15502
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