Verrucous epidermal nevus as a manifestation of a type 2 mosaic PTEN mutation in Cowden syndrome

Linear Cowden nevus, also known as linear PTEN nevus, is a type of epidermal nevus, first described in 2007, which is seen in patients with PTEN hamartoma tumor syndrome. It is considered to be a type 2 form of segmental mosaicism, and we suggest that it has certain clinical features that distinguis...

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Autores principales: Plana‐Pla, Adrià, Condal, Laura, Jaka, Ane, Blanco, Ignacio, Castellanos, Elisabeth, Bielsa, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087675/
https://www.ncbi.nlm.nih.gov/pubmed/36151877
http://dx.doi.org/10.1111/pde.15116
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author Plana‐Pla, Adrià
Condal, Laura
Jaka, Ane
Blanco, Ignacio
Castellanos, Elisabeth
Bielsa, Isabel
author_facet Plana‐Pla, Adrià
Condal, Laura
Jaka, Ane
Blanco, Ignacio
Castellanos, Elisabeth
Bielsa, Isabel
author_sort Plana‐Pla, Adrià
collection PubMed
description Linear Cowden nevus, also known as linear PTEN nevus, is a type of epidermal nevus, first described in 2007, which is seen in patients with PTEN hamartoma tumor syndrome. It is considered to be a type 2 form of segmental mosaicism, and we suggest that it has certain clinical features that distinguish it from epidermal nevi seen in similar conditions, such as Proteus syndrome. We present a case of linear Cowden nevus in a 4‐year‐old boy and review the literature.
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spelling pubmed-100876752023-04-12 Verrucous epidermal nevus as a manifestation of a type 2 mosaic PTEN mutation in Cowden syndrome Plana‐Pla, Adrià Condal, Laura Jaka, Ane Blanco, Ignacio Castellanos, Elisabeth Bielsa, Isabel Pediatr Dermatol Case Reports Linear Cowden nevus, also known as linear PTEN nevus, is a type of epidermal nevus, first described in 2007, which is seen in patients with PTEN hamartoma tumor syndrome. It is considered to be a type 2 form of segmental mosaicism, and we suggest that it has certain clinical features that distinguish it from epidermal nevi seen in similar conditions, such as Proteus syndrome. We present a case of linear Cowden nevus in a 4‐year‐old boy and review the literature. John Wiley and Sons Inc. 2022-09-24 2023 /pmc/articles/PMC10087675/ /pubmed/36151877 http://dx.doi.org/10.1111/pde.15116 Text en © 2022 The Authors. Pediatric Dermatology published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Plana‐Pla, Adrià
Condal, Laura
Jaka, Ane
Blanco, Ignacio
Castellanos, Elisabeth
Bielsa, Isabel
Verrucous epidermal nevus as a manifestation of a type 2 mosaic PTEN mutation in Cowden syndrome
title Verrucous epidermal nevus as a manifestation of a type 2 mosaic PTEN mutation in Cowden syndrome
title_full Verrucous epidermal nevus as a manifestation of a type 2 mosaic PTEN mutation in Cowden syndrome
title_fullStr Verrucous epidermal nevus as a manifestation of a type 2 mosaic PTEN mutation in Cowden syndrome
title_full_unstemmed Verrucous epidermal nevus as a manifestation of a type 2 mosaic PTEN mutation in Cowden syndrome
title_short Verrucous epidermal nevus as a manifestation of a type 2 mosaic PTEN mutation in Cowden syndrome
title_sort verrucous epidermal nevus as a manifestation of a type 2 mosaic pten mutation in cowden syndrome
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087675/
https://www.ncbi.nlm.nih.gov/pubmed/36151877
http://dx.doi.org/10.1111/pde.15116
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