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Targeting glucose‐6‐phosphate dehydrogenase by 6‐AN induces ROS‐mediated autophagic cell death in breast cancer

Dysregulation of G6PD involved in the pentose phosphate pathway (PPP) is known to promote tumorigenesis. The PPP plays a pivotal role in meeting the anabolic demands of cancer cells. However, the detailed underlying molecular mechanisms of targeting the G6PD‐regulated PPP in breast cancer remain unc...

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Detalles Bibliográficos
Autores principales: Li, Yin, Zheng, Fangxu, Zhang, Yupeng, Lin, Zhoujun, Yang, Juan, Han, Xiao, Feng, Ya, Pei, Xiaolin, Li, Fei, Liu, Qiao, Yan, Lizhong, Li, Tianjiao, Zhang, Yifan, Li, Ding, Fu, Zhenkun, Wang, Changjun, Sun, Qiang, Li, Chenggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087799/
https://www.ncbi.nlm.nih.gov/pubmed/36048131
http://dx.doi.org/10.1111/febs.16614