Cargando…

The phospholipid flippase ATP8B1 is required for lysosomal fusion in macrophages

ATP8B1 is a phospholipid flippase and member of the type 4 subfamily of P‐type ATPases (P4‐ATPase) subfamily. P4‐ATPases catalyze the translocation of phospholipids across biological membranes, ensuring proper membrane asymmetry, which is crucial for membrane protein targeting and activity, vesicle...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gómez‐Mellado, Valentina E., Ho‐Mok, Kam S., van der Mark, Vincent A., van der Wel, Nicole N., Grootemaat, Anita E., Verhoeven, Arthur J., Elferink, Ronald P. J. Oude, Paulusma, Coen C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087937/ https://www.ncbi.nlm.nih.gov/pubmed/36169099 http://dx.doi.org/10.1002/cbf.3752

Ejemplares similares

P4 ATPases: Flippases in Health and Disease
por: van der Mark, Vincent A., et al.
Publicado: (2013)

Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4
por: van der Mark, Vincent A., et al.
Publicado: (2016)

ATP8B1 Deficiency Results in Elevated Mitochondrial Phosphatidylethanolamine Levels and Increased Mitochondrial Oxidative Phosphorylation in Human Hepatoma Cells
por: Gómez-Mellado, Valentina E., et al.
Publicado: (2022)

Alteration of viral lipid composition by expression of the phospholipid floppase ABCB4 reduces HIV vector infectivity
por: van Til, Niek P, et al.
Publicado: (2008)

The Drosophila melanogaster Phospholipid Flippase dATP8B Is Required for Odorant Receptor Function
por: Liu, Yu-Chi, et al.
Publicado: (2014)

The phospholipid flippase ATP9A is required for the recycling pathway from the endosomes to the plasma membrane
por: Tanaka, Yoshiki, et al.
Publicado: (2016)

Regulation of phospholipid distribution in the lipid bilayer by flippases and scramblases
por: Sakuragi, Takaharu, et al.
Publicado: (2023)

Phospholipid flippases and Sfk1 are essential for the retention of ergosterol in the plasma membrane
por: Kishimoto, Takuma, et al.
Publicado: (2021)

P4-ATPases as Phospholipid Flippases—Structure, Function, and Enigmas
por: Andersen, Jens P., et al.
Publicado: (2016)

Phospholipid flippase ATP11C is endocytosed and downregulated following Ca(2+)-mediated protein kinase C activation
por: Takatsu, Hiroyuki, et al.
Publicado: (2017)

C-terminus of the P4-ATPase ATP8A2 functions in protein folding and regulation of phospholipid flippase activity
por: Chalat, Madhavan, et al.
Publicado: (2017)

Asymmetric distribution of phosphatidylserine is generated in the absence of phospholipid flippases in Saccharomyces cerevisiae
por: Mioka, Tetsuo, et al.
Publicado: (2014)

Inositol Depletion Restores Vesicle Transport in Yeast Phospholipid Flippase Mutants
por: Yamagami, Kanako, et al.
Publicado: (2015)

Blocking Sodium‐Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice
por: Roscam Abbing, Reinout L.P., et al.
Publicado: (2019)

Phospholipid flippases and Sfk1p, a novel regulator of phospholipid asymmetry, contribute to low permeability of the plasma membrane
por: Mioka, Tetsuo, et al.
Publicado: (2018)

The phospholipid flippase ALA3 regulates pollen tube growth and guidance in Arabidopsis
por: Yang, Yang, et al.
Publicado: (2022)

Strain Background Modifies Phenotypes in the ATP8B1-Deficient Mouse
por: Shah, Sohela, et al.
Publicado: (2010)

Gain-of-Function Mutations in the Phospholipid Flippase MprF Confer Specific Daptomycin Resistance
por: Ernst, Christoph M., et al.
Publicado: (2018)

An optogenetic system to control membrane phospholipid asymmetry through flippase activation in budding yeast
por: Suzuki, Tomomi, et al.
Publicado: (2020)

A malaria parasite phospholipid flippase safeguards midgut traversal of ookinetes for mosquito transmission
por: Yang, Zhenke, et al.
Publicado: (2021)

Cryo-EM of the ATP11C flippase reconstituted in Nanodiscs shows a distended phospholipid bilayer inner membrane around transmembrane helix 2
por: Nakanishi, Hanayo, et al.
Publicado: (2021)

Extracellular vesicle budding is inhibited by redundant regulators of TAT-5 flippase localization and phospholipid asymmetry
por: Beer, Katharina B., et al.
Publicado: (2018)

Proteomic Analysis and Functional Characterization of P4-ATPase Phospholipid Flippases from Murine Tissues
por: Wang, Jiao, et al.
Publicado: (2018)

Disease Mutation Study Identifies Critical Residues for Phosphatidylserine Flippase ATP11A
por: Sun, Kuanxiang, et al.
Publicado: (2020)

Physiological and Pathological Functions of TMEM30A: An Essential Subunit of P4-ATPase Phospholipid Flippases
por: Li, Jingyi, et al.
Publicado: (2023)

Deficiency of the lipid flippase ATP10A causes diet-induced dyslipidemia in female mice
por: Norris, Adriana C., et al.
Publicado: (2023)

Soluble Adenylyl Cyclase Regulates Bile Salt‐Induced Apoptosis in Human Cholangiocytes
por: Chang, Jung‐Chin, et al.
Publicado: (2016)

The P4-ATPase ATP9A is a novel determinant of exosome release
por: Naik, Jyoti, et al.
Publicado: (2019)

Cfs1p, a Novel Membrane Protein in the PQ-Loop Family, Is Involved in Phospholipid Flippase Functions in Yeast
por: Yamamoto, Takaharu, et al.
Publicado: (2016)

Autosomal dominant non-syndromic hearing loss maps to DFNA33 (13q34) and co-segregates with splice and frameshift variants in ATP11A, a phospholipid flippase gene
por: Pater, Justin A., et al.
Publicado: (2022)

Glycochenodeoxycholate Promotes Liver Fibrosis in Mice with Hepatocellular Cholestasis
por: Hohenester, Simon, et al.
Publicado: (2020)

Transfer dynamics of multi-resistance plasmids in Escherichia coli isolated from meat
por: Darphorn, Tania S., et al.
Publicado: (2022)

ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome–lysosome fusion
por: Wang, Ruoxi, et al.
Publicado: (2019)

PUB11-Dependent Ubiquitination of the Phospholipid Flippase ALA10 Modifies ALA10 Localization and Affects the Pool of Linolenic Phosphatidylcholine
por: Salvaing, Juliette, et al.
Publicado: (2020)

Structural insights into the activation of autoinhibited human lipid flippase ATP8B1 upon substrate binding
por: Cheng, Meng-Ting, et al.
Publicado: (2022)

Lipid Flippases for Bacterial Peptidoglycan Biosynthesis
por: Ruiz, Natividad
Publicado: (2016)

Reply
por: Roscam Abbing, Reinout L.P., et al.
Publicado: (2020)

Regulation of membrane phospholipid asymmetry by Notch-mediated flippase expression controls the number of intraepithelial TCRαβ(+)CD8αα(+) T cells
por: Ishifune, Chieko, et al.
Publicado: (2019)

A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages
por: Bedard, Melissa, et al.
Publicado: (2023)

Autoinhibition and regulation by phosphoinositides of ATP8B1, a human lipid flippase associated with intrahepatic cholestatic disorders
por: Dieudonné, Thibaud, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_d3hrk800tkrhm6bld1npjv209a