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Alpinetin alleviates osteoporosis by promoting osteogenic differentiation in BMSCs by triggering autophagy via PKA/mTOR/ULK1 signaling

Osteoporosis, a systemic bone disease that is characterized by a reduction in bone mass and destruction of bone microstructure, is becoming a serious problem worldwide. Bone marrow mesenchymal stem cells (BMSCs) can differentiate into bone‐forming osteoblasts, and play an important role in maintaini...

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Detalles Bibliográficos
Autores principales: Zeng, Chenying, Wang, Shan, Chen, Fenglei, Wang, Ziming, Li, Jinteng, Xie, Zhongyu, Ma, Mengjun, Wang, Peng, Shen, Huiyong, Wu, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087978/
https://www.ncbi.nlm.nih.gov/pubmed/36104214
http://dx.doi.org/10.1002/ptr.7610