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Normal Alpha-1-Antitrypsin Variants Display in Serum Allele-Specific Protein Levels

[Image: see text] Alpha-1-antitrypsin (A1AT or SERPINA1) has been proposed as a putative biomarker distinguishing healthy from diseased donors throughout several proteomics studies. However, the SERPINA1 gene displays high variability of frequent occurring genotypes among the general population. The...

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Detalles Bibliográficos
Autores principales: Jager, Shelley, Cramer, Dario A. T., Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088046/
https://www.ncbi.nlm.nih.gov/pubmed/36946534
http://dx.doi.org/10.1021/acs.jproteome.2c00833