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Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer
BACKGROUND: About 5–10% of breast cancer cases are attributed to a gene mutation. To perform preventive interventions for women with a gene mutation, genetic screening BRCA tests have recently been implemented in Iran. The present study aimed to determine Iranian women’s subjective valuation for scr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088156/ https://www.ncbi.nlm.nih.gov/pubmed/37041634 http://dx.doi.org/10.1186/s12889-023-15568-0 |
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author | Meshkani, Zahra Moradi, Najmeh Aboutorabi, Ali Jafari, Abdosaleh Shams, Roshanak |
author_facet | Meshkani, Zahra Moradi, Najmeh Aboutorabi, Ali Jafari, Abdosaleh Shams, Roshanak |
author_sort | Meshkani, Zahra |
collection | PubMed |
description | BACKGROUND: About 5–10% of breast cancer cases are attributed to a gene mutation. To perform preventive interventions for women with a gene mutation, genetic screening BRCA tests have recently been implemented in Iran. The present study aimed to determine Iranian women’s subjective valuation for screening BRCA tests for early detection of breast cancer to help policymakers to make decisions about genetic screening tests for breast cancer and to know the applicants. METHODS: An online survey was completed by women older than 30 years old in Tehran, the capital of Iran in 2021. A hypothetical scenario about genetic screening tests for breast cancer was defined. The subjective valuation for the tests was assessed by a willingness to pay (WTP) using the contingent valuation method (CVM) by payment card. Demographics, history of breast cancers, knowledge, and physiological variables were considered as independent variables, and a logistic regression model assessed the relationship between WTP and the variables. RESULTS: 660 women were included. 88% of participants intended to participate in BRCA genetic screening for breast cancer if it were free. The mean WTP for the tests was about $ 20. Based on the logistic regression, income, family history of breast or ovarian cancer, and positive attitude were associated with WTP. CONCLUSIONS: Iranian women were willing to intend for genetic screening BRCA tests and pay for them as well. The result of the present study is of great importance for policy makers when it comes to funding and determining co-payments for BRCA genetic screening tests. To achieve a high participation rate of women in breast cancer screening plans, a positive attitude should be promoted as a psychological factor. Educational and informative programs can help. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-023-15568-0. |
format | Online Article Text |
id | pubmed-10088156 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-100881562023-04-12 Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer Meshkani, Zahra Moradi, Najmeh Aboutorabi, Ali Jafari, Abdosaleh Shams, Roshanak BMC Public Health Research BACKGROUND: About 5–10% of breast cancer cases are attributed to a gene mutation. To perform preventive interventions for women with a gene mutation, genetic screening BRCA tests have recently been implemented in Iran. The present study aimed to determine Iranian women’s subjective valuation for screening BRCA tests for early detection of breast cancer to help policymakers to make decisions about genetic screening tests for breast cancer and to know the applicants. METHODS: An online survey was completed by women older than 30 years old in Tehran, the capital of Iran in 2021. A hypothetical scenario about genetic screening tests for breast cancer was defined. The subjective valuation for the tests was assessed by a willingness to pay (WTP) using the contingent valuation method (CVM) by payment card. Demographics, history of breast cancers, knowledge, and physiological variables were considered as independent variables, and a logistic regression model assessed the relationship between WTP and the variables. RESULTS: 660 women were included. 88% of participants intended to participate in BRCA genetic screening for breast cancer if it were free. The mean WTP for the tests was about $ 20. Based on the logistic regression, income, family history of breast or ovarian cancer, and positive attitude were associated with WTP. CONCLUSIONS: Iranian women were willing to intend for genetic screening BRCA tests and pay for them as well. The result of the present study is of great importance for policy makers when it comes to funding and determining co-payments for BRCA genetic screening tests. To achieve a high participation rate of women in breast cancer screening plans, a positive attitude should be promoted as a psychological factor. Educational and informative programs can help. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-023-15568-0. BioMed Central 2023-04-11 /pmc/articles/PMC10088156/ /pubmed/37041634 http://dx.doi.org/10.1186/s12889-023-15568-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Meshkani, Zahra Moradi, Najmeh Aboutorabi, Ali Jafari, Abdosaleh Shams, Roshanak Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer |
title | Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer |
title_full | Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer |
title_fullStr | Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer |
title_full_unstemmed | Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer |
title_short | Subjective valuation of Iranian women for screening for gene-related diseases: a case of breast cancer |
title_sort | subjective valuation of iranian women for screening for gene-related diseases: a case of breast cancer |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088156/ https://www.ncbi.nlm.nih.gov/pubmed/37041634 http://dx.doi.org/10.1186/s12889-023-15568-0 |
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