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METTL3 enhances dentinogenesis differentiation of dental pulp stem cells via increasing GDF6 and STC1 mRNA stability

BACKGROUND: The dentinogenesis differentiation of dental pulp stem cells (DPSCs) is controlled by the spatio-temporal expression of differentiation related genes. RNA N6-methyladenosine (m(6)A) methylation, one of the most abundant internal epigenetic modification in mRNA, influences various events...

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Detalles Bibliográficos
Autores principales: Pan, Yue, Liu, Ying, Cui, Dixin, Yu, Sihan, Zhou, Yachuan, Zhou, Xin, Du, Wei, Zheng, Liwei, Wan, Mian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088233/
https://www.ncbi.nlm.nih.gov/pubmed/37041485
http://dx.doi.org/10.1186/s12903-023-02836-z