Structural basis of spike RBM-specific human antibodies counteracting broad SARS-CoV-2 variants

The decrease of antibody efficacy to mutated SARS-CoV-2 spike RBD explains the breakthrough infections and reinfections by Omicron variants. Here, we analyzed broadly neutralizing antibodies isolated from long-term hospitalized convalescent patients of early SARS-CoV-2 strains. One of the antibodies...

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Detalles Bibliográficos
Autores principales: Shitaoka, Kiyomi, Higashiura, Akifumi, Kawano, Yohei, Yamamoto, Akima, Mizoguchi, Yoko, Hashiguchi, Takao, Nishimichi, Norihisa, Huang, Shiyu, Ito, Ayano, Ohki, Shun, Kanda, Miyuki, Taniguchi, Tomohiro, Yoshizato, Rin, Azuma, Hitoshi, Kitajima, Yasuo, Yokosaki, Yasuyuki, Okada, Satoshi, Sakaguchi, Takemasa, Yasuda, Tomoharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088672/
https://www.ncbi.nlm.nih.gov/pubmed/37041231
http://dx.doi.org/10.1038/s42003-023-04782-6

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