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A Novel Approach Utilizing Machine Learning for the Early Diagnosis of Alzheimer's Disease

Alzheimer's disease (AD) is one of the leading causes of dementia among older people. In addition, a considerable portion of the world's population suffers from metabolic problems, such as Alzheimer's disease and diabetes. Alzheimer's disease affects the brain in a degenerative m...

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Autores principales: Uddin, Khandaker Mohammad Mohi, Alam, Mir Jafikul, Jannat-E-Anawar, Uddin, Md Ashraf, Aryal, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088738/
https://www.ncbi.nlm.nih.gov/pubmed/37363136
http://dx.doi.org/10.1007/s44174-023-00078-9
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author Uddin, Khandaker Mohammad Mohi
Alam, Mir Jafikul
Jannat-E-Anawar
Uddin, Md Ashraf
Aryal, Sunil
author_facet Uddin, Khandaker Mohammad Mohi
Alam, Mir Jafikul
Jannat-E-Anawar
Uddin, Md Ashraf
Aryal, Sunil
author_sort Uddin, Khandaker Mohammad Mohi
collection PubMed
description Alzheimer's disease (AD) is one of the leading causes of dementia among older people. In addition, a considerable portion of the world's population suffers from metabolic problems, such as Alzheimer's disease and diabetes. Alzheimer's disease affects the brain in a degenerative manner. As the elderly population grows, this illness can cause more people to become inactive by impairing their memory and physical functionality. This might impact their family members and the financial, economic, and social spheres. Researchers have recently investigated different machine learning and deep learning approaches to detect such diseases at an earlier stage. Early diagnosis and treatment of AD help patients to recover from it successfully and with the least harm. This paper proposes a machine learning model that comprises GaussianNB, Decision Tree, Random Forest, XGBoost, Voting Classifier, and GradientBoost to predict Alzheimer's disease. The model is trained using the open access series of imaging studies (OASIS) dataset to evaluate the performance in terms of accuracy, precision, recall, and F1 score. Our findings showed that the voting classifier attained the highest validation accuracy of 96% for the AD dataset. Therefore, ML algorithms have the potential to drastically lower Alzheimer's disease annual mortality rates through accurate detection.
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spelling pubmed-100887382023-04-12 A Novel Approach Utilizing Machine Learning for the Early Diagnosis of Alzheimer's Disease Uddin, Khandaker Mohammad Mohi Alam, Mir Jafikul Jannat-E-Anawar Uddin, Md Ashraf Aryal, Sunil Biomed Mater Devices Original Article Alzheimer's disease (AD) is one of the leading causes of dementia among older people. In addition, a considerable portion of the world's population suffers from metabolic problems, such as Alzheimer's disease and diabetes. Alzheimer's disease affects the brain in a degenerative manner. As the elderly population grows, this illness can cause more people to become inactive by impairing their memory and physical functionality. This might impact their family members and the financial, economic, and social spheres. Researchers have recently investigated different machine learning and deep learning approaches to detect such diseases at an earlier stage. Early diagnosis and treatment of AD help patients to recover from it successfully and with the least harm. This paper proposes a machine learning model that comprises GaussianNB, Decision Tree, Random Forest, XGBoost, Voting Classifier, and GradientBoost to predict Alzheimer's disease. The model is trained using the open access series of imaging studies (OASIS) dataset to evaluate the performance in terms of accuracy, precision, recall, and F1 score. Our findings showed that the voting classifier attained the highest validation accuracy of 96% for the AD dataset. Therefore, ML algorithms have the potential to drastically lower Alzheimer's disease annual mortality rates through accurate detection. Springer US 2023-04-10 /pmc/articles/PMC10088738/ /pubmed/37363136 http://dx.doi.org/10.1007/s44174-023-00078-9 Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Article
Uddin, Khandaker Mohammad Mohi
Alam, Mir Jafikul
Jannat-E-Anawar
Uddin, Md Ashraf
Aryal, Sunil
A Novel Approach Utilizing Machine Learning for the Early Diagnosis of Alzheimer's Disease
title A Novel Approach Utilizing Machine Learning for the Early Diagnosis of Alzheimer's Disease
title_full A Novel Approach Utilizing Machine Learning for the Early Diagnosis of Alzheimer's Disease
title_fullStr A Novel Approach Utilizing Machine Learning for the Early Diagnosis of Alzheimer's Disease
title_full_unstemmed A Novel Approach Utilizing Machine Learning for the Early Diagnosis of Alzheimer's Disease
title_short A Novel Approach Utilizing Machine Learning for the Early Diagnosis of Alzheimer's Disease
title_sort novel approach utilizing machine learning for the early diagnosis of alzheimer's disease
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088738/
https://www.ncbi.nlm.nih.gov/pubmed/37363136
http://dx.doi.org/10.1007/s44174-023-00078-9
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