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A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix
Treating a diabetic foot ulcer (DFU) extending to the tendon or bone can be a challenge for physicians. Recent studies have shown positive results of micronized acellular dermal matrix (ADM) treatment for treating DFU. However, studies on such ADM with a long‐term follow‐up are rare. Thus, the objec...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088852/ https://www.ncbi.nlm.nih.gov/pubmed/36377547 http://dx.doi.org/10.1111/iwj.14018 |
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author | Byeon, Je Yeon Hwang, Yong Seon Choi, Hwan Jun Kim, Jun Hyuk Lee, Da Woon |
author_facet | Byeon, Je Yeon Hwang, Yong Seon Choi, Hwan Jun Kim, Jun Hyuk Lee, Da Woon |
author_sort | Byeon, Je Yeon |
collection | PubMed |
description | Treating a diabetic foot ulcer (DFU) extending to the tendon or bone can be a challenge for physicians. Recent studies have shown positive results of micronized acellular dermal matrix (ADM) treatment for treating DFU. However, studies on such ADM with a long‐term follow‐up are rare. Thus, the objective of this study was to retrospectively analyse patients treated with micronized ADM with a long‐term follow‐up to assess the effectiveness of the treatment and determine the recurrence rate. The rate of success of complete healing was 62.96% and the time of complete healing was 86.96 days in this study. The recurrence rate of DFUs was 41.17% in the overall group. However, it was only 23.52% in the micronized ADM group. The average duration of recurrence was 720.50 ± 505.12 days. The recurrence rate was 50% in weight bearing areas such as the plantar and heel. It was 12.5% in toes and non‐weight bearing areas. In conclusion, micronized ADM can be used to effectively treat DFUs that have invaded ligaments or bones. A close follow‐up of weight bearing area wounds will allow us to identify and treat recurrence early. |
format | Online Article Text |
id | pubmed-10088852 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Blackwell Publishing Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-100888522023-04-12 A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix Byeon, Je Yeon Hwang, Yong Seon Choi, Hwan Jun Kim, Jun Hyuk Lee, Da Woon Int Wound J Original Articles Treating a diabetic foot ulcer (DFU) extending to the tendon or bone can be a challenge for physicians. Recent studies have shown positive results of micronized acellular dermal matrix (ADM) treatment for treating DFU. However, studies on such ADM with a long‐term follow‐up are rare. Thus, the objective of this study was to retrospectively analyse patients treated with micronized ADM with a long‐term follow‐up to assess the effectiveness of the treatment and determine the recurrence rate. The rate of success of complete healing was 62.96% and the time of complete healing was 86.96 days in this study. The recurrence rate of DFUs was 41.17% in the overall group. However, it was only 23.52% in the micronized ADM group. The average duration of recurrence was 720.50 ± 505.12 days. The recurrence rate was 50% in weight bearing areas such as the plantar and heel. It was 12.5% in toes and non‐weight bearing areas. In conclusion, micronized ADM can be used to effectively treat DFUs that have invaded ligaments or bones. A close follow‐up of weight bearing area wounds will allow us to identify and treat recurrence early. Blackwell Publishing Ltd 2022-11-15 /pmc/articles/PMC10088852/ /pubmed/36377547 http://dx.doi.org/10.1111/iwj.14018 Text en © 2022 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Original Articles Byeon, Je Yeon Hwang, Yong Seon Choi, Hwan Jun Kim, Jun Hyuk Lee, Da Woon A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix |
title | A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix |
title_full | A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix |
title_fullStr | A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix |
title_full_unstemmed | A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix |
title_short | A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix |
title_sort | long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088852/ https://www.ncbi.nlm.nih.gov/pubmed/36377547 http://dx.doi.org/10.1111/iwj.14018 |
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