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A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix

Treating a diabetic foot ulcer (DFU) extending to the tendon or bone can be a challenge for physicians. Recent studies have shown positive results of micronized acellular dermal matrix (ADM) treatment for treating DFU. However, studies on such ADM with a long‐term follow‐up are rare. Thus, the objec...

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Autores principales: Byeon, Je Yeon, Hwang, Yong Seon, Choi, Hwan Jun, Kim, Jun Hyuk, Lee, Da Woon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088852/
https://www.ncbi.nlm.nih.gov/pubmed/36377547
http://dx.doi.org/10.1111/iwj.14018
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author Byeon, Je Yeon
Hwang, Yong Seon
Choi, Hwan Jun
Kim, Jun Hyuk
Lee, Da Woon
author_facet Byeon, Je Yeon
Hwang, Yong Seon
Choi, Hwan Jun
Kim, Jun Hyuk
Lee, Da Woon
author_sort Byeon, Je Yeon
collection PubMed
description Treating a diabetic foot ulcer (DFU) extending to the tendon or bone can be a challenge for physicians. Recent studies have shown positive results of micronized acellular dermal matrix (ADM) treatment for treating DFU. However, studies on such ADM with a long‐term follow‐up are rare. Thus, the objective of this study was to retrospectively analyse patients treated with micronized ADM with a long‐term follow‐up to assess the effectiveness of the treatment and determine the recurrence rate. The rate of success of complete healing was 62.96% and the time of complete healing was 86.96 days in this study. The recurrence rate of DFUs was 41.17% in the overall group. However, it was only 23.52% in the micronized ADM group. The average duration of recurrence was 720.50 ± 505.12 days. The recurrence rate was 50% in weight bearing areas such as the plantar and heel. It was 12.5% in toes and non‐weight bearing areas. In conclusion, micronized ADM can be used to effectively treat DFUs that have invaded ligaments or bones. A close follow‐up of weight bearing area wounds will allow us to identify and treat recurrence early.
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spelling pubmed-100888522023-04-12 A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix Byeon, Je Yeon Hwang, Yong Seon Choi, Hwan Jun Kim, Jun Hyuk Lee, Da Woon Int Wound J Original Articles Treating a diabetic foot ulcer (DFU) extending to the tendon or bone can be a challenge for physicians. Recent studies have shown positive results of micronized acellular dermal matrix (ADM) treatment for treating DFU. However, studies on such ADM with a long‐term follow‐up are rare. Thus, the objective of this study was to retrospectively analyse patients treated with micronized ADM with a long‐term follow‐up to assess the effectiveness of the treatment and determine the recurrence rate. The rate of success of complete healing was 62.96% and the time of complete healing was 86.96 days in this study. The recurrence rate of DFUs was 41.17% in the overall group. However, it was only 23.52% in the micronized ADM group. The average duration of recurrence was 720.50 ± 505.12 days. The recurrence rate was 50% in weight bearing areas such as the plantar and heel. It was 12.5% in toes and non‐weight bearing areas. In conclusion, micronized ADM can be used to effectively treat DFUs that have invaded ligaments or bones. A close follow‐up of weight bearing area wounds will allow us to identify and treat recurrence early. Blackwell Publishing Ltd 2022-11-15 /pmc/articles/PMC10088852/ /pubmed/36377547 http://dx.doi.org/10.1111/iwj.14018 Text en © 2022 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Byeon, Je Yeon
Hwang, Yong Seon
Choi, Hwan Jun
Kim, Jun Hyuk
Lee, Da Woon
A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix
title A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix
title_full A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix
title_fullStr A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix
title_full_unstemmed A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix
title_short A long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix
title_sort long‐term follow‐up study of diabetic foot ulcer using micronized acellular dermal matrix
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088852/
https://www.ncbi.nlm.nih.gov/pubmed/36377547
http://dx.doi.org/10.1111/iwj.14018
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