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Decompression Surgery Options for Metastatic Cervical Spine Lesions

Background: Metastatic spinal lesions occur in 70% of patients with incurable cancer, and the most common site for bone metastases is the spine. Over the last decade, medical science has made significant progress in treating tumor damage to the spine. The study examined the efficacy of decompression...

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Autores principales: Gorbacheva, Liubov, Potapov, Mikhail, Taran, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088883/
https://www.ncbi.nlm.nih.gov/pubmed/37056392
http://dx.doi.org/10.7150/jca.81594
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author Gorbacheva, Liubov
Potapov, Mikhail
Taran, Vadim
author_facet Gorbacheva, Liubov
Potapov, Mikhail
Taran, Vadim
author_sort Gorbacheva, Liubov
collection PubMed
description Background: Metastatic spinal lesions occur in 70% of patients with incurable cancer, and the most common site for bone metastases is the spine. Over the last decade, medical science has made significant progress in treating tumor damage to the spine. The study examined the efficacy of decompression surgery for patients with metastatic cervical spine lesions contributing to spinal cord compression. Methods: The study enrolled 38 patients (27 females and 11 males, average age of 61.35±8.49 years) with metastatic cervical spine lesions resulting in cord compression relieved with surgery. Patients experienced improvement in pain and motor within one month of surgery addressing cervical metastatic disease. Results: Complete or partial regression of pain syndrome 10 days after surgery was observed in 26 (68.4%) patients, one month later - in 33 (86.8%) patients, one year later - in 35 (92.1%) patients. Regression of neurological symptoms on the 10th day after surgery was observed in 8 (21.1%) patients, one month later - in 21 (55.3%) patients, one year later - in 34 (89.5%) patients. Two patients died between 3 and 12 months after surgery, having a worsening of their neurological status and pain syndrome. Conclusions: Decompression surgeries for metastatic lesions of the cervical spine with spinal cord compression resulted in effective reduction of pain and neurological dysfunction.
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spelling pubmed-100888832023-04-12 Decompression Surgery Options for Metastatic Cervical Spine Lesions Gorbacheva, Liubov Potapov, Mikhail Taran, Vadim J Cancer Research Paper Background: Metastatic spinal lesions occur in 70% of patients with incurable cancer, and the most common site for bone metastases is the spine. Over the last decade, medical science has made significant progress in treating tumor damage to the spine. The study examined the efficacy of decompression surgery for patients with metastatic cervical spine lesions contributing to spinal cord compression. Methods: The study enrolled 38 patients (27 females and 11 males, average age of 61.35±8.49 years) with metastatic cervical spine lesions resulting in cord compression relieved with surgery. Patients experienced improvement in pain and motor within one month of surgery addressing cervical metastatic disease. Results: Complete or partial regression of pain syndrome 10 days after surgery was observed in 26 (68.4%) patients, one month later - in 33 (86.8%) patients, one year later - in 35 (92.1%) patients. Regression of neurological symptoms on the 10th day after surgery was observed in 8 (21.1%) patients, one month later - in 21 (55.3%) patients, one year later - in 34 (89.5%) patients. Two patients died between 3 and 12 months after surgery, having a worsening of their neurological status and pain syndrome. Conclusions: Decompression surgeries for metastatic lesions of the cervical spine with spinal cord compression resulted in effective reduction of pain and neurological dysfunction. Ivyspring International Publisher 2023-04-01 /pmc/articles/PMC10088883/ /pubmed/37056392 http://dx.doi.org/10.7150/jca.81594 Text en © The author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Research Paper
Gorbacheva, Liubov
Potapov, Mikhail
Taran, Vadim
Decompression Surgery Options for Metastatic Cervical Spine Lesions
title Decompression Surgery Options for Metastatic Cervical Spine Lesions
title_full Decompression Surgery Options for Metastatic Cervical Spine Lesions
title_fullStr Decompression Surgery Options for Metastatic Cervical Spine Lesions
title_full_unstemmed Decompression Surgery Options for Metastatic Cervical Spine Lesions
title_short Decompression Surgery Options for Metastatic Cervical Spine Lesions
title_sort decompression surgery options for metastatic cervical spine lesions
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088883/
https://www.ncbi.nlm.nih.gov/pubmed/37056392
http://dx.doi.org/10.7150/jca.81594
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