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Focal Boundary Dice: Improved Breast Tumor Segmentation from MRI Scan

Focal Boundary Dice, a new segmentation evaluation measure, was hereby presented, with the focus on boundary quality and class imbalance. Extensive analysis was carried out across different error types with varied object sizes of imaged tumors from Magnetic Resonance Imaging (MRI) scans, and the res...

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Autores principales: Yin, Xiao-Xia, Jian, Yunxiang, Shen, Jing, Wu, Jianlin, Zhang, Yanchun, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088889/
https://www.ncbi.nlm.nih.gov/pubmed/37056389
http://dx.doi.org/10.7150/jca.82592
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author Yin, Xiao-Xia
Jian, Yunxiang
Shen, Jing
Wu, Jianlin
Zhang, Yanchun
Wang, Wei
author_facet Yin, Xiao-Xia
Jian, Yunxiang
Shen, Jing
Wu, Jianlin
Zhang, Yanchun
Wang, Wei
author_sort Yin, Xiao-Xia
collection PubMed
description Focal Boundary Dice, a new segmentation evaluation measure, was hereby presented, with the focus on boundary quality and class imbalance. Extensive analysis was carried out across different error types with varied object sizes of imaged tumors from Magnetic Resonance Imaging (MRI) scans, and the results show that Focal Boundary Dice is significantly more adaptive than the standard Focal and Dice measures to boundary errors for imaged tumors from MRI scans and does not over-penalize errors on the division of the boundary, including smaller imaged objects. Based on Boundary Dice, the standard evaluation protocols for tumor segmentation tasks were updated by proposing the Focal Boundary Dice. The contradiction between the target and the background area, and the conflict between the importance and the attention of boundary features were mainly solved. Meanwhile, a boundary attention module was introduced to further extract the tumor edge features. The new quality measure presents several desirable characteristics, including higher accuracy in the selection of hard samples, prediction/ground-truth pairs, and balanced responsiveness with across scales, which jointly make it more suitable for segmentation evaluation than other classification-focused measures such as combined Intersection-over-Union and Boundary binary cross-entropy loss, Boundary binary cross-entropy loss and Shape-aware Loss. The experiments show that the new evaluation metrics allow boundary quality improvements and image segmentation accuracy that are generally overlooked by current Dice-based evaluation metrics and deep learning models. It is expected that the adoption of the new boundary-adaptive evaluation metrics will facilitate the rapid progress in segmentation methods, and further contribute to the improvement of classification accuracy.
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spelling pubmed-100888892023-04-12 Focal Boundary Dice: Improved Breast Tumor Segmentation from MRI Scan Yin, Xiao-Xia Jian, Yunxiang Shen, Jing Wu, Jianlin Zhang, Yanchun Wang, Wei J Cancer Research Paper Focal Boundary Dice, a new segmentation evaluation measure, was hereby presented, with the focus on boundary quality and class imbalance. Extensive analysis was carried out across different error types with varied object sizes of imaged tumors from Magnetic Resonance Imaging (MRI) scans, and the results show that Focal Boundary Dice is significantly more adaptive than the standard Focal and Dice measures to boundary errors for imaged tumors from MRI scans and does not over-penalize errors on the division of the boundary, including smaller imaged objects. Based on Boundary Dice, the standard evaluation protocols for tumor segmentation tasks were updated by proposing the Focal Boundary Dice. The contradiction between the target and the background area, and the conflict between the importance and the attention of boundary features were mainly solved. Meanwhile, a boundary attention module was introduced to further extract the tumor edge features. The new quality measure presents several desirable characteristics, including higher accuracy in the selection of hard samples, prediction/ground-truth pairs, and balanced responsiveness with across scales, which jointly make it more suitable for segmentation evaluation than other classification-focused measures such as combined Intersection-over-Union and Boundary binary cross-entropy loss, Boundary binary cross-entropy loss and Shape-aware Loss. The experiments show that the new evaluation metrics allow boundary quality improvements and image segmentation accuracy that are generally overlooked by current Dice-based evaluation metrics and deep learning models. It is expected that the adoption of the new boundary-adaptive evaluation metrics will facilitate the rapid progress in segmentation methods, and further contribute to the improvement of classification accuracy. Ivyspring International Publisher 2023-03-13 /pmc/articles/PMC10088889/ /pubmed/37056389 http://dx.doi.org/10.7150/jca.82592 Text en © The author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Research Paper
Yin, Xiao-Xia
Jian, Yunxiang
Shen, Jing
Wu, Jianlin
Zhang, Yanchun
Wang, Wei
Focal Boundary Dice: Improved Breast Tumor Segmentation from MRI Scan
title Focal Boundary Dice: Improved Breast Tumor Segmentation from MRI Scan
title_full Focal Boundary Dice: Improved Breast Tumor Segmentation from MRI Scan
title_fullStr Focal Boundary Dice: Improved Breast Tumor Segmentation from MRI Scan
title_full_unstemmed Focal Boundary Dice: Improved Breast Tumor Segmentation from MRI Scan
title_short Focal Boundary Dice: Improved Breast Tumor Segmentation from MRI Scan
title_sort focal boundary dice: improved breast tumor segmentation from mri scan
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088889/
https://www.ncbi.nlm.nih.gov/pubmed/37056389
http://dx.doi.org/10.7150/jca.82592
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