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Nanopore sequencing reveals methylation changes associated with obesity in circulating cell-free DNA from Göttingen Minipigs

Profiling of circulating cell-free DNA (cfDNA) by tissue-specific base modifications, such as 5-methylcytosines (5mC), may enable the monitoring of ongoing pathophysiological processes. Nanopore sequencing allows genome-wide 5mC detection in cfDNA without bisulphite conversion. The aims of this stud...

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Detalles Bibliográficos
Autores principales:	Drag, Markus Hodal, Debes, Karina Poulsdóttir, Franck, Clara Sandkamm, Flethøj, Mette, Lyhne, Mille Kronborg, Møller, Jacob Eifer, Ludvigsen, Trine Pagh, Jespersen, Thomas, Olsen, Lisbeth Høier, Kilpeläinen, Tuomas O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088973/ https://www.ncbi.nlm.nih.gov/pubmed/37032646 http://dx.doi.org/10.1080/15592294.2023.2199374

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