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Liver Cirrhosis among Young Adults Admitted to the Department of Gastroenterology in a Tertiary Care Centre: A Descriptive Cross-sectional Study

INTRODUCTION: Cirrhosis in young adults is an important health problem worldwide and is a common disease. Patients usually present late in a decompensated state with varied complications. However, national data on the exact burden of the disease is lacking. The aim of this study was to find out the...

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Autores principales: Bhusal, Mohan, Pathak, Rahul, Bhandari, Brindeswari Kafle, Jha, Anurag, Hamal, Rabin, Koirala, Dinesh, Lamsal, Manoj, Kafle, Pradip Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088990/
https://www.ncbi.nlm.nih.gov/pubmed/37203980
http://dx.doi.org/10.31729/jnma.8016
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author Bhusal, Mohan
Pathak, Rahul
Bhandari, Brindeswari Kafle
Jha, Anurag
Hamal, Rabin
Koirala, Dinesh
Lamsal, Manoj
Kafle, Pradip Kumar
author_facet Bhusal, Mohan
Pathak, Rahul
Bhandari, Brindeswari Kafle
Jha, Anurag
Hamal, Rabin
Koirala, Dinesh
Lamsal, Manoj
Kafle, Pradip Kumar
author_sort Bhusal, Mohan
collection PubMed
description INTRODUCTION: Cirrhosis in young adults is an important health problem worldwide and is a common disease. Patients usually present late in a decompensated state with varied complications. However, national data on the exact burden of the disease is lacking. The aim of this study was to find out the prevalence of liver cirrhosis among young adults admitted to the Department of Gastroenterology in a tertiary care centre. METHODS: A descriptive cross-sectional study was done among patients admitted to the Department of Gastroenterology in a tertiary care centre between 25 November 2021 to 30 November 2022 after receiving ethical approval from the Institutional Review Committee [Reference number: 227(6-11) E2-078/079]. Convenience sampling was done. Point estimate and 95% Confidence Interval were calculated. RESULTS: Among 989 patients, liver cirrhosis in young adults was seen in 200 (20.22%) (18.12-22.32, 95% Confidence Interval). Chronic alcohol use was the primary cause of cirrhosis seen in 164 (82%) cases. The most typical presenting symptom was abdominal distension seen in 187 (93.50%) patients. The most frequent complication was ascites seen in 184 (92%) patients. The most frequent endoscopic finding was gastro-oesophagal varices seen in 180 (90%) patients. There were 145 (72.50%) men and 55 (27.50%) women. CONCLUSIONS: The prevalence of liver cirrhosis in young adults was found to be lower than the other studies done in similar settings.
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spelling pubmed-100889902023-04-12 Liver Cirrhosis among Young Adults Admitted to the Department of Gastroenterology in a Tertiary Care Centre: A Descriptive Cross-sectional Study Bhusal, Mohan Pathak, Rahul Bhandari, Brindeswari Kafle Jha, Anurag Hamal, Rabin Koirala, Dinesh Lamsal, Manoj Kafle, Pradip Kumar JNMA J Nepal Med Assoc Original Article INTRODUCTION: Cirrhosis in young adults is an important health problem worldwide and is a common disease. Patients usually present late in a decompensated state with varied complications. However, national data on the exact burden of the disease is lacking. The aim of this study was to find out the prevalence of liver cirrhosis among young adults admitted to the Department of Gastroenterology in a tertiary care centre. METHODS: A descriptive cross-sectional study was done among patients admitted to the Department of Gastroenterology in a tertiary care centre between 25 November 2021 to 30 November 2022 after receiving ethical approval from the Institutional Review Committee [Reference number: 227(6-11) E2-078/079]. Convenience sampling was done. Point estimate and 95% Confidence Interval were calculated. RESULTS: Among 989 patients, liver cirrhosis in young adults was seen in 200 (20.22%) (18.12-22.32, 95% Confidence Interval). Chronic alcohol use was the primary cause of cirrhosis seen in 164 (82%) cases. The most typical presenting symptom was abdominal distension seen in 187 (93.50%) patients. The most frequent complication was ascites seen in 184 (92%) patients. The most frequent endoscopic finding was gastro-oesophagal varices seen in 180 (90%) patients. There were 145 (72.50%) men and 55 (27.50%) women. CONCLUSIONS: The prevalence of liver cirrhosis in young adults was found to be lower than the other studies done in similar settings. Journal of the Nepal Medical Association 2023-02 2023-02-28 /pmc/articles/PMC10088990/ /pubmed/37203980 http://dx.doi.org/10.31729/jnma.8016 Text en © The Author(s) 2018. https://creativecommons.org/licenses/by/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Bhusal, Mohan
Pathak, Rahul
Bhandari, Brindeswari Kafle
Jha, Anurag
Hamal, Rabin
Koirala, Dinesh
Lamsal, Manoj
Kafle, Pradip Kumar
Liver Cirrhosis among Young Adults Admitted to the Department of Gastroenterology in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title Liver Cirrhosis among Young Adults Admitted to the Department of Gastroenterology in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_full Liver Cirrhosis among Young Adults Admitted to the Department of Gastroenterology in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_fullStr Liver Cirrhosis among Young Adults Admitted to the Department of Gastroenterology in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_full_unstemmed Liver Cirrhosis among Young Adults Admitted to the Department of Gastroenterology in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_short Liver Cirrhosis among Young Adults Admitted to the Department of Gastroenterology in a Tertiary Care Centre: A Descriptive Cross-sectional Study
title_sort liver cirrhosis among young adults admitted to the department of gastroenterology in a tertiary care centre: a descriptive cross-sectional study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088990/
https://www.ncbi.nlm.nih.gov/pubmed/37203980
http://dx.doi.org/10.31729/jnma.8016
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