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Adenosquamous Carcinoma of Gallbladder with Unusual Prognosis: A Case Report

The adenosquamous carcinoma of the gallbladder is a rare variant accounting for only 1-4% of all primary gallbladder carcinoma. Regardless of the histological types, all gallbladder carcinomas have silent and rapid progression resulting in delayed diagnosis and poor prognosis. Even with medical and/...

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Autores principales: Gyawali, Siddinath, Pokhrel, Biraj, Sharma, Deepak, Bhatta, Naveen Chandra, Kandel, Bishnu Prasad, Lakhey, Paleswan Joshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089038/
https://www.ncbi.nlm.nih.gov/pubmed/37203927
http://dx.doi.org/10.31729/jnma.7923
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author Gyawali, Siddinath
Pokhrel, Biraj
Sharma, Deepak
Bhatta, Naveen Chandra
Kandel, Bishnu Prasad
Lakhey, Paleswan Joshi
author_facet Gyawali, Siddinath
Pokhrel, Biraj
Sharma, Deepak
Bhatta, Naveen Chandra
Kandel, Bishnu Prasad
Lakhey, Paleswan Joshi
author_sort Gyawali, Siddinath
collection PubMed
description The adenosquamous carcinoma of the gallbladder is a rare variant accounting for only 1-4% of all primary gallbladder carcinoma. Regardless of the histological types, all gallbladder carcinomas have silent and rapid progression resulting in delayed diagnosis and poor prognosis. Even with medical and/or surgical interventions, the median survival of patients with adenosquamous carcinoma, one of the histological variants, is less than a year. However, we present a case of adenosquamous carcinoma with an unusually better prognosis. A 70-year-old female patient, after being diagnosed with gallbladder carcinoma was suggested for surgical resection but was lost to follow-up since then. Two years later, the patient presented and was managed with extended cholecystectomy. The slow progression and non-recurrence of the tumour during follow-up for two years after the surgery indicates a better prognosis in this case.
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spelling pubmed-100890382023-04-12 Adenosquamous Carcinoma of Gallbladder with Unusual Prognosis: A Case Report Gyawali, Siddinath Pokhrel, Biraj Sharma, Deepak Bhatta, Naveen Chandra Kandel, Bishnu Prasad Lakhey, Paleswan Joshi JNMA J Nepal Med Assoc Case Report The adenosquamous carcinoma of the gallbladder is a rare variant accounting for only 1-4% of all primary gallbladder carcinoma. Regardless of the histological types, all gallbladder carcinomas have silent and rapid progression resulting in delayed diagnosis and poor prognosis. Even with medical and/or surgical interventions, the median survival of patients with adenosquamous carcinoma, one of the histological variants, is less than a year. However, we present a case of adenosquamous carcinoma with an unusually better prognosis. A 70-year-old female patient, after being diagnosed with gallbladder carcinoma was suggested for surgical resection but was lost to follow-up since then. Two years later, the patient presented and was managed with extended cholecystectomy. The slow progression and non-recurrence of the tumour during follow-up for two years after the surgery indicates a better prognosis in this case. Journal of the Nepal Medical Association 2023-01 2023-01-31 /pmc/articles/PMC10089038/ /pubmed/37203927 http://dx.doi.org/10.31729/jnma.7923 Text en © The Author(s) 2018. https://creativecommons.org/licenses/by/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gyawali, Siddinath
Pokhrel, Biraj
Sharma, Deepak
Bhatta, Naveen Chandra
Kandel, Bishnu Prasad
Lakhey, Paleswan Joshi
Adenosquamous Carcinoma of Gallbladder with Unusual Prognosis: A Case Report
title Adenosquamous Carcinoma of Gallbladder with Unusual Prognosis: A Case Report
title_full Adenosquamous Carcinoma of Gallbladder with Unusual Prognosis: A Case Report
title_fullStr Adenosquamous Carcinoma of Gallbladder with Unusual Prognosis: A Case Report
title_full_unstemmed Adenosquamous Carcinoma of Gallbladder with Unusual Prognosis: A Case Report
title_short Adenosquamous Carcinoma of Gallbladder with Unusual Prognosis: A Case Report
title_sort adenosquamous carcinoma of gallbladder with unusual prognosis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10089038/
https://www.ncbi.nlm.nih.gov/pubmed/37203927
http://dx.doi.org/10.31729/jnma.7923
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